Effective Therapies for Chronic Pancreatitis: What Works?
Published: Feb 11, 2024
Finding the right therapy for chronic pancreatitis is crucial for improving quality of life. Let's explore the options available for managing this condition.
Contents
Therapies for Pain Management
Managing pain is a significant focus of therapy for chronic pancreatitis. Non-opioid medications are the first line of treatment, with opioids considered only if necessary. Adjunctive therapies, including antidepressants, can enhance pain relief and address coexisting depression.
Addressing Digestive Issues
Pancreatic enzyme replacement therapy is essential for those with exocrine pancreatic insufficiency. This therapy helps manage malabsorption and improves nutritional status. Regular monitoring and adjustments can optimize the effectiveness of this treatment.

Managing Diabetes
Diabetes resulting from chronic pancreatitis, known as type 3c diabetes, requires careful management. Metformin is often used, but insulin may also be necessary. Monitoring blood glucose levels and adjusting treatment is crucial for preventing complications.
Frequently Asked Questions
Non-opioid medications are the first step.
They help with digestion and nutrient absorption.
Yes, they can enhance pain relief.
It's diabetes caused by chronic pancreatitis.
The Bottom Line
Effective therapy requires a combination of treatments tailored to individual needs.
References
- Anderson MA, Akshintala V, Albers KM, et al. Mechanism, assessment and management of pain in chronic pancreatitis: Recommendations of a multidisciplinary study group. Pancreatology 2016; 16:83.
- Ahmed Ali U, Jens S, Busch OR, et al. Antioxidants for pain in chronic pancreatitis. Cochrane Database Syst Rev 2014; :CD008945.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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