Can Medication Ease the Pain of Chronic Pancreatitis?
Published: Mar 15, 2024
Medications are often needed to manage the pain associated with chronic pancreatitis. Let's dive into how different drugs can help relieve this pain.
Contents
Starting with Non-Opioid Options
Pain management usually begins with non-opioid medications like NSAIDs and acetaminophen. These drugs are effective for many and provide a safer option compared to stronger pain medications. The goal is to manage pain effectively while minimizing the use of opioids.
When Opioids Are Necessary
If non-opioid medications fail, opioids may be prescribed. It's critical to use the lowest effective dose and to monitor for any signs of dependency. Tramadol is often used as it has dual-action properties and provides similar relief to stronger opioids.

Adjunctive Therapies
Adjunctive agents like tricyclic antidepressants and SSRIs can be used alongside opioids to enhance pain management. These can also help address any coexisting depression, which is common in chronic pancreatitis patients.
Frequently Asked Questions
No, they are used if non-opioid options fail.
Acetaminophen is a common choice.
Yes, they can enhance pain relief and treat depression.
Yes, it provides relief similar to stronger opioids.
Wrapping Up
Effective pain management requires a combination of medications tailored to each individual.
References
- Nusrat S, Yadav D, Bielefeldt K. Pain and opioid use in chronic pancreatitis. Pancreas 2012; 41:264.
- World Health Organization. Cancer pain relief: with a guide to opioid availability, 2nd ed, Geneva 1996.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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