Are You at Risk for Primary Hyperparathyroidism?

Published: Nov 08, 2023

Identifying risk factors for primary hyperparathyroidism can help you take action before symptoms develop.

Genetic Predispositions

Some people inherit a genetic risk for primary hyperparathyroidism. Conditions like Multiple Endocrine Neoplasia (MEN) and Familial Isolated Hyperparathyroidism are linked to genetic mutations that increase risk. If you have a family history of such conditions, genetic testing might be recommended.

Environmental and Lifestyle Factors

Exposure to radiation and certain chemicals can increase your risk of developing primary hyperparathyroidism. Lifestyle factors, such as low calcium intake, can also contribute by causing chronic stimulation of the parathyroid gland. Ensuring adequate calcium intake and minimizing radiation exposure can help mitigate these risks.

Primary hyperparathyroidism is a condition characterized by the overproduction of parathyroid hormone due to genetic predispositions or lifestyle factors. It can lead to various symptoms related to high calcium levels.

Medications and Other Medical Conditions

Certain medications, such as lithium, can affect calcium and parathyroid hormone levels, increasing the risk of hyperparathyroidism. Additionally, conditions like chronic kidney disease may contribute to altered calcium metabolism, enhancing susceptibility. Regular medical check-ups can help monitor and manage these risks.

Frequently Asked Questions

Genetic factors, radiation exposure, and certain medications can increase risk.

Yes, low calcium intake can increase risk by overstimulating the parathyroid gland.

Yes, genetic tests can identify mutations linked to the condition.

Some medications like lithium can increase the risk of hyperparathyroidism.

Key Takeaways

Understanding your risk factors for primary hyperparathyroidism can help you take proactive steps to manage your health.

Discuss your personal risk factors with Doctronic to find out more.

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References

Minisola S, Arnold A, Belaya Z, et al. Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism. J Bone Miner Res 2022; 37:2315.

Pollak MR, Brown EM, Chou YH, et al. Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 1993; 75:1297.

Always discuss health information with your healthcare provider.