Are You at Risk for Polyneuropathy? Key Factors to Know
Published: Jun 23, 2024
Certain factors can increase your risk for developing polyneuropathy. Recognizing these can help you take proactive steps to protect your nerve health.
Contents
Diabetes and Lifestyle
One of the most significant risk factors for polyneuropathy is diabetes, particularly when blood sugar levels are not well-controlled. Other lifestyle factors, like excessive alcohol consumption, can also damage nerves and increase risk. Adopting a healthy lifestyle can mitigate these risks.
Genetic and Autoimmune Factors
Genetics play a role in some cases of polyneuropathy, like Charcot-Marie-Tooth disease. Autoimmune conditions, where the body's immune system attacks its own nerves, also contribute to risk. Understanding family history and autoimmune tendencies can be crucial in assessing risk.

Medication and Environmental Exposures
Certain medications and environmental toxins can lead to nerve damage, raising the risk for polyneuropathy. Chemotherapy drugs and exposure to heavy metals are common culprits. Being aware of these factors can help in taking preventive measures.
Frequently Asked Questions
Diabetes, alcohol use, and certain medications can increase risk.
Yes, some forms like Charcot-Marie-Tooth are hereditary.
Yes, certain drugs, especially chemotherapy drugs, can damage nerves.
Yes, exposure to toxins like heavy metals can increase risk.
The Bottom Line
Recognizing risk factors for polyneuropathy is key to prevention and early intervention.
References
- Callaghan BC, Price RS, Feldman EL. Distal Symmetric Polyneuropathy: A Review. JAMA 2015; 314:2172.
- Singer MA, Vernino SA, Wolfe GI. Idiopathic neuropathy: new paradigms, new promise. J Peripher Nerv Syst 2012; 17 Suppl 2:43.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
15-min consultation. No hidden costs.
AI Doctor Visit Required
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?