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Medically reviewed by Jerome Albert Ecker | MD, Assistant Professor of Medicine, Duke University - Durham, NC on October 19th, 2023.
Neurogenic TOS affects 95% of cases, primarily compressing the brachial plexus nerves and occurring 3-4 times more frequently in women aged 20-50 than men.
Symptoms typically worsen with overhead arm positions and can progress from intermittent tingling to permanent nerve damage within months if untreated.
Anatomical variations like cervical ribs (present in 0.5-1% of the population) or abnormal first rib positioning create the narrow space where compression occurs.
Conservative treatment succeeds in 85% of patients within 3-6 months, focusing on strengthening middle trapezius and rhomboid muscles while stretching anterior scalenes.
Surgical intervention becomes necessary when patients develop muscle atrophy in the hand, persistent vascular symptoms, or fail to improve after 6 months of physical therapy.
Thoracic outlet syndrome (TOS) is a condition that occurs when the nerves, blood vessels, or muscles in the space between your lower neck and upper chest (thoracic outlet) become compressed. This compression can lead to pain, numbness, and tingling in your arms and shoulders, especially when you raise your arms. TOS is more common in women and can affect anyone, particularly athletes and workers who perform repetitive arm motions.
There are three main types of TOS:
Neurogenic TOS: Affects the nerves leading from the spinal cord to the neck and arm. This is the most common type, accounting for about 95% of cases.
Venous TOS: Affects the veins in the thoracic outlet area.
Arterial TOS: Affects the arteries in the thoracic outlet area. This type is rare but more serious.
Symptoms of TOS are most often felt in the arms and hands, and may include:
Pain in the neck, shoulder, or arm
Numbness and tingling
Swelling
Weakness
Discoloration (blue, red, or pale skin)
Cold hands
Muscle atrophy (wasting) in the arm
Weak pulse in the affected arm
Painful lump near the collarbone
Shrinking of the muscle at the base of the thumb (Gilliatt-Sumner hand)
Several factors can contribute to the development of TOS, including:
Injuries (e.g., whiplash, broken collarbone)
Poor posture (rounded shoulders)
Repetitive stress from certain arm movements
Physical defects (e.g., extra rib, smaller thoracic outlet)
Obesity
Pregnancy
Sleep disorders
Tumors in the upper chest or under the arm
Stress or depression
Cervical rib
Blood clots or Aneurysm
Catheter use
Carrying heavy bags on the shoulder
Diagnosing TOS can be challenging, as symptoms may be similar to other conditions such as arthritis, pinched nerves, or carpal tunnel syndrome. Your doctor will begin with a detailed history of your symptoms and a physical exam. They may also recommend various tests, including:
Positioning tests
Scalene muscle block
Imaging tests (e.g., X-ray, CT scan, MRI, ultrasound)
Nerve tests
Blood circulation tests (e.g., arteriogram, venogram)
Treatment for TOS depends on the specific type and severity of the condition. For neurogenic TOS, treatment may include:
Physical therapy to stretch and strengthen muscles, and improve posture
Medications (e.g., muscle relaxants, NSAIDs) to relieve pain and swelling
Botox injections to relax muscles at the base of the neck
Surgery, in some cases
For venous and arterial TOS, treatment typically involves addressing any blood clots and performing thoracic outlet decompression surgery to create more space for nerves and blood vessels.
In addition to medical treatment, your doctor may recommend lifestyle changes and home remedies to help manage TOS, such as maintaining a healthy weight, setting up an ergonomic workstation, taking frequent breaks, and practicing relaxation techniques.
If left untreated, TOS can lead to serious complications, including chronic pain, nerve damage, blood flow problems, and blood clots. It is essential to seek prompt medical attention if you experience symptoms of TOS.
For more information on thoracic outlet syndrome, visit:
Early recognition and treatment prevent the progression from reversible nerve irritation to permanent muscle weakness and sensory loss. Most patients recover fully with targeted physical therapy and ergonomic modifications within 6 months. If you're experiencing arm pain or numbness that worsens with overhead activities, Doctronic can help evaluate your symptoms quickly.
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