Should You Take Statins Over 75? A Guide to Cholesterol Medication for Seniors

If you're over 75, you may be wondering if you should start taking a statin medication to lower your cholesterol and reduce your risk of heart disease. While statins can be beneficial for many people, the decision to start this medication becomes more complex as we age. In this article, we'll explore the factors to consider when deciding whether statins are right for you.

What Are Statins and How Do They Work?

Statins are a class of medications that work by blocking an enzyme in the liver responsible for producing cholesterol. By reducing the amount of cholesterol your body makes, statins can help lower your risk of developing atherosclerotic cardiovascular disease (ASCVD), which includes conditions like heart attack, peripheral vascular disease (PAD), and stroke.

The Potential Benefits of Statins for Seniors

According to a study published in the Annals of Internal Medicine, treating all adults aged 75 to 94 with statins could potentially prevent 105,000 heart attacks and 68,000 deaths from coronary artery disease over a 10-year period. This is because the risk of ASCVD increases with age, and the majority of deaths from these conditions occur in older adults.

Factors to Consider When Deciding on Statin Use

While the potential benefits of statins are significant, there are several important factors to consider before starting this medication:

• The importance of cholesterol as a risk factor for ASCVD decreases with age

• Older adults are at increased risk for adverse effects from statins, such as muscle pain and fatigue

• Statins may interact with other medications commonly taken by seniors

• Other chronic health conditions may be as likely as ASCVD to contribute to functional decline and cause death

Making an Informed Decision with Your Doctor

If you're over 75 and don't have ASCVD, it's important to have a conversation with your doctor about whether starting a statin makes sense for you. Your doctor can help you weigh the potential benefits and risks based on your individual health status and medical history.

Recommendations by Age Group

• Over 75 with ASCVD: Continue statin or start if new ASCVD or DM is discovered

• Over age 75 and in good health: The decision is individualized, considering overall health status and preferences

• Limited Life Expectancy: Consider deprescribing

• Over 85 (healthy or not): The benefits may no longer outweigh the risks and side effects

• Those with chronic illnesses and multiple medications: Be cautious, as side effects may negate the statin's benefits

Remember, the decision to start a statin should be made in partnership with your healthcare provider. They can help you make an informed choice based on your unique circumstances and health goals. For more information on heart health and cholesterol management, visit the American Heart Association, National Heart, Lung, and Blood Institute, or Centers for Disease Control and Prevention websites.