Understanding Rheumatic Fever: Symptoms, Causes, and Treatment Options

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on July 12th, 2023.

Key Takeaways

  • This autoimmune condition develops 1-5 weeks after untreated group A streptococcal infections when antibodies meant to fight bacteria mistakenly attack heart, joints, brain, and skin tissues.
  • Joint pain typically migrates between large joints (knees, elbows, ankles, wrists) over several days, while Sydenham's chorea causes involuntary jerky movements that can persist for months.
  • Children aged 5-15 in crowded conditions face highest risk, with the condition being rare in developed countries due to widespread antibiotic use—affecting less than 1 in 100,000 people annually in the US.
  • Acute treatment requires high-dose aspirin (80-100 mg/kg/day) for joint inflammation, plus penicillin to eliminate remaining bacteria, with corticosteroids reserved for severe heart involvement.
  • Long-term penicillin prophylaxis is essential—monthly injections or daily oral doses for 10+ years depending on heart damage severity, as recurrent episodes cause progressively worse valve damage.

Rheumatic fever is a serious illness that can occur when strep throat or scarlet fever, caused by group A streptococcus bacteria, is not treated properly. While rare in developed countries, cases have recently increased in the United States, particularly among children in poor urban areas. It's essential to be aware of the symptoms, causes, and treatment options for this potentially life-threatening condition.

Symptoms of Rheumatic Fever

Symptoms of rheumatic fever usually appear 1-5 weeks after an untreated strep throat or scarlet fever infection. Some common symptoms include:

  • Swollen, tender, red, and painful joints, especially in the knees, ankles, elbows, or wrists

  • Fever

  • A red, raised, lattice-like rash on the chest, back, and abdomen

  • Small bumps (nodules) over the swollen joints

  • Chest pain, fast heartbeat, or shortness of breath, which may indicate heart involvement

  • Uncontrollable jerky movements of the arms, legs, or facial muscles (chorea)

Causes and Risk Factors

Rheumatic fever occurs when the body's immune system mistakenly attacks its own tissues in response to a group A streptococcus infection. While anyone who has had strep throat, scarlet fever, or impetigo can develop rheumatic fever, some people are at a higher risk, including:

  • Children aged 5-15 years

  • People in large groups, such as schools, daycare centers, and military training facilities

  • Those who have had rheumatic fever in the past and get strep throat, scarlet fever, or impetigo again

Understanding Rheumatic Fever: Symptoms, Causes, and Treatment Options

Diagnosing Rheumatic Fever

To diagnose rheumatic fever, your doctor will perform a throat culture to check for the presence of streptococcus bacteria. They will also conduct a complete exam, listening to your heart for signs of trouble and looking for other symptoms like arthritis in multiple joints and small nodules on the joints. Additional tests may include:

  • Blood tests to check for antibodies related to a recent group A strep infection

  • Electrocardiogram (EKG) to assess heart function

  • Echocardiography (echo) to visualize the heart muscle in action

Treatment Options

Treatment for rheumatic fever typically involves a combination of antibiotics to eliminate the bacteria, anti-inflammatory medications to reduce swelling and pain, and plenty of rest. In severe cases, surgery may be necessary to repair heart valve damage and prevent heart failure. Long-term antibiotic treatment may be required to prevent recurrence.

It's crucial to seek medical attention if you suspect you or your child has rheumatic fever. Early diagnosis and treatment can help prevent serious complications, such as rheumatic heart disease, which can lead to heart valve damage and irregular heartbeat.

For more information on rheumatic fever, consult trusted sources like the Centers for Disease Control and Prevention (CDC) and the American Heart Association.

The Bottom Line

Prevention through prompt strep throat treatment with antibiotics is critical, as this immune system reaction can cause permanent heart valve damage requiring lifelong monitoring. Once diagnosed, strict adherence to long-term antibiotic prophylaxis prevents devastating recurrences. If you're experiencing joint pain, fever, or unusual movements after a recent sore throat, Doctronic can help evaluate your symptoms quickly.

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