Dulaglutide Dosage Guide: How Much to Take and When (With Chart)

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on January 3rd, 2026.

Key Takeaways

  • Dulaglutide is a once-weekly injectable medication primarily used to manage type 2 diabetes.
  • Typical adult doses start at 0.75 mg once weekly, with possible increases to 1.5 mg or higher based on response.
  • Children are generally not prescribed dulaglutide, as safety and efficacy data are limited in pediatric populations.
  • Dulaglutide should be administered subcutaneously, and timing should be consistent each week.
  • Missed doses should be taken as soon as possible within 3 days; otherwise, skip and resume the next scheduled dose.
  • Adjustments may be required for patients with kidney or liver impairment, under medical guidance.
  • For personalized dosage advice and telehealth consultations, Doctronic.ai offers expert support 24/7.

Understanding Dulaglutide Uses and Dosages

Dulaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used to improve blood sugar control in adults with type 2 diabetes. Its once-weekly dosing makes it more convenient than daily injections. However, understanding the correct dosage and timing is crucial to maximizing benefits and minimizing side effects.

This guide breaks down dulaglutide dosages, how to adjust them, and what to do if you miss a dose. It also highlights when to seek professional advice and how telehealth services like Doctronic.ai can help tailor your treatment plan.

Dulaglutide Dosage Chart

Form

Strength

Typical Adult Dose

Typical Children’s Dose

Frequency

Route

Maximum Daily Dose

Injection

0.75 mg/0.5 mL

0.75 mg once weekly (initial dose)

Not typically prescribed

Once weekly

Subcutaneous

4.5 mg/week

Injection

1.5 mg/0.5 mL

1.5 mg once weekly (maintenance dose)

Not typically prescribed

Once weekly

Subcutaneous

4.5 mg/week

Injection

3 mg/0.5 mL

3 mg once weekly (dose escalation)

Not typically prescribed

Once weekly

Subcutaneous

4.5 mg/week

Injection

4.5 mg/0.5 mL

4.5 mg once weekly (maximum dose)

Not typically prescribed

Once weekly

Subcutaneous

4.5 mg/week

What is the Typical Dulaglutide Dose For Adults?

Adults starting dulaglutide usually begin with a 0.75 mg injection once a week. This initial dose helps the body adjust and reduces the risk of side effects such as nausea.

After 4 weeks, if blood sugar control is insufficient, the dose can be increased to 1.5 mg once weekly. Some patients may require higher doses of 3 mg or 4.5 mg weekly, which are approved for further glycemic control improvement.

Dulaglutide is administered subcutaneously in the abdomen, thigh, or upper arm. Consistency in the day of the week for injections helps maintain steady medication levels.

What is the Typical Dulaglutide Dose For Children?

Dulaglutide is not typically prescribed for children or adolescents under 18 years old. The safety and effectiveness of dulaglutide in pediatric patients have not been established. When managing diabetes in younger populations, alternative therapies are usually considered.

What to Do If You Miss a Dose of Dulaglutide?

If a dulaglutide dose is missed, it should be taken as soon as possible if within 3 days (72 hours) of the missed dose. If more than 3 days have passed, skip the missed dose and take the next scheduled dose on the usual day.

Never take two doses within 3 days to make up for a missed injection. Doing so may increase the risk of side effects.

How to Adjust Your Dulaglutide Dose For Certain Medical Conditions

Kidney Impairment Adjustment

Dulaglutide can be used in patients with mild to moderate kidney impairment without dose adjustment. However, patients with severe kidney problems should use dulaglutide cautiously and under close medical supervision.

Liver Disease Adjustment

There is limited data on dulaglutide use in severe liver disease. Patients with mild to moderate hepatic impairment typically do not require dose changes, but close monitoring is advised.

Other Conditions

Patients with gastrointestinal diseases such as gastroparesis should consult their healthcare provider before starting dulaglutide due to the potential worsening of symptoms.

Dulaglutide Overdose and Warnings

An overdose of dulaglutide can lead to severe nausea, vomiting, and hypoglycemia (low blood sugar). If an overdose is suspected, seek emergency medical attention immediately.

Patients should be aware of potential side effects, including pancreatitis, thyroid tumors, and allergic reactions. Always discuss any new symptoms with your healthcare provider promptly.

Tips For Taking Dulaglutide Safely

  • Store dulaglutide in the refrigerator until first use, then store it at room temperature for up to 14 days.

  • Use a new needle for each injection to reduce the risk of infection.

  • Rotate injection sites to avoid skin irritation.

  • Inform your healthcare provider about all medications and supplements you take to avoid interactions.

  • Monitor blood sugar regularly and report any unusual changes.

Learn More About Dulaglutide Dosage With Doctronic

Understanding the proper dulaglutide dosage for your unique health situation can be complex. Personalized advice is vital, especially when managing chronic conditions like diabetes. Doctronic.ai offers free AI-powered doctor visits that synthesize the latest peer-reviewed medical research tailored to your needs.

With Doctronic, you can get quick, accurate answers about your medication, dosage adjustments, and treatment options. If needed, connect instantly with licensed doctors through affordable telehealth video visits available 24/7 across all 50 states. This makes managing your diabetes easier and more convenient.

Person checking blood sugar using a glucose meter, with a test strip touching their fingertip

Frequently Asked Questions

Yes, dulaglutide is often used alongside other diabetes drugs like metformin. However, combining medications should always be supervised by a healthcare provider to avoid interactions and hypoglycemia.

Many patients notice improved blood sugar control within the first few weeks, but full effects may take several months as your body adjusts.

No. Dose increases should only be made under medical supervision to ensure safety and effectiveness.

Common side effects include nausea, injection site reactions, diarrhea, and mild gastrointestinal discomfort. If side effects are severe or persistent, contact your healthcare provider promptly.

Yes, many patients experience weight loss while on dulaglutide, which can be beneficial in managing type 2 diabetes.

Doctronic.ai provides AI-driven answers and access to licensed doctors who can help personalize your dosage and treatment plan at any time.

References

The Bottom Line

Dulaglutide is a powerful tool in managing type 2 diabetes, offering the convenience of once-weekly dosing and effective blood sugar control. Starting at a low dose and adjusting according to your response helps minimize side effects and optimize benefits.

Always follow your healthcare provider’s instructions and consult them if you experience any issues or have questions about your dosage. For personalized guidance and easy access to medical professionals, consider using Doctronic.ai to support your diabetes management journey.

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