Does Plan B Work? Understanding Emergency Contraception Effectiveness

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on February 6th, 2026.

Key Takeaways

  • Plan B prevents up to 89% of potential pregnancies when taken within 72 hours

  • Effectiveness decreases significantly after 24-48 hours

  • Body weight and timing can impact emergency contraception performance

  • Follow-up with regular birth control is recommended

Emergency contraception represents an important reproductive health option for individuals seeking to prevent unintended pregnancy. Plan B One-Step offers a critical backup method when primary contraception fails or is unavailable. Understanding its mechanisms, effectiveness, and potential limitations can help individuals make informed healthcare decisions.

How Plan B Works in Your Body

Plan B contains levonorgestrel, a synthetic hormone that primarily prevents pregnancy by stopping or delaying ovulation. When taken before an egg is released, the medication can effectively block fertilization. It works by altering the reproductive environment, making birth control more strategic and responsive.

The hormone is quickly absorbed, reaching peak blood levels within two hours of ingestion. Importantly, Plan B is not an abortion medication but a preventive measure that intervenes before pregnancy can be established.

Effectiveness Rates and Timing

Plan B's effectiveness is dramatically time-sensitive. Here's a breakdown of prevention rates:

Timing After Intercourse

Pregnancy Prevention Rate

First 24 hours

95%

24-48 hours

85%

48-72 hours

58%

72-120 hours

Approximately 50%

Factors Affecting Effectiveness

Multiple variables can impact Plan B's performance. Body weight is a significant consideration, with reduced effectiveness potentially occurring in individuals over 165 pounds. Healthcare providers recommend consulting a medical professional for personalized guidance.

Certain medications can also interfere with Plan B, including:

  • Anticonvulsants

  • Rifampin antibiotics

  • St. John's Wort supplements

Side Effects and Expectations

Most individuals experience temporary side effects such as:

  • Menstrual cycle changes

  • Nausea

  • Fatigue

  • Headache

  • Abdominal discomfort

  • Vomiting

  • Dizziness

  • Fatigue

  • Breast tenderness

Frequently Asked Questions

Is Plan B 100% effective?

No emergency contraception is 100% guaranteed. Plan B prevents approximately 89% of potential pregnancies.

How soon should I take Plan B?

The sooner, the better. Effectiveness is highest within the first 24 hours after unprotected intercourse.

Can I use Plan B as regular birth control?

No, it's designed for emergency use only. Regular birth control methods are more reliable and consistent.

Does weight impact Plan B's effectiveness?

Yes, individuals over 165 pounds may experience reduced effectiveness.

What if I vomit after taking Plan B?

Consult a healthcare provider. Vomiting within two hours might require another dose.

The Bottom Line

Emergency contraception provides an important reproductive health option, but it's not a substitute for regular birth control. Care you can trust. Doctronic is clinically validated with 99% treatment plan alignment.

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