Understanding Comprehensive Metabolic Panel (CMP) Blood Tests

A comprehensive metabolic panel (CMP) is a blood test that measures 14 different substances in your blood. It provides important information about your body's chemical balance and metabolism, including liver and kidney function, blood sugar (glucose) levels, and electrolyte and fluid balance. The CMP is a routine test that can help detect a wide range of disorders, such as diabetes, liver disease, and kidney disease.

What Does a CMP Measure?

The 14 tests included in a CMP are:

  • Albumin: a protein made by the liver

  • Alkaline phosphatase (ALP): an enzyme found in the liver, bones, and other tissues

  • Alanine aminotransferase (ALT): an enzyme mainly found in the liver

  • Aspartate aminotransferase (AST): an enzyme found in the liver and other tissues

  • Bilirubin: a waste product from the breakdown of red blood cells

  • Blood urea nitrogen (BUN): a waste product filtered out by the kidneys

  • Calcium: a mineral essential for bones, muscles, and nerves

  • Carbon dioxide: a measure of bicarbonate, an electrolyte that helps maintain pH balance

  • Chloride: an electrolyte that helps regulate fluid balance

  • Creatinine: a waste product from muscle breakdown filtered out by the kidneys

  • Glucose: blood sugar, the body's main source of energy

  • Potassium: an electrolyte needed for proper nerve and muscle function

  • Sodium: an electrolyte that helps regulate blood pressure and fluid balance

  • Total protein: measures albumin and all other proteins in blood

Why Is a CMP Done?

A CMP may be ordered as part of a routine medical exam or to help:

  • Diagnose liver, kidney, or other disorders

  • Monitor treatment for diabetes, high blood pressure, liver disease, and kidney disease

  • Check for side effects of medications

  • Assess overall health

Your doctor may also order a CMP if you have symptoms that suggest a liver disorder, kidney problem, or other metabolic disorder.

How Is a CMP Done?

A CMP requires a small blood sample, which is usually drawn from a vein in your arm. You may need to fast for 8-12 hours before the test to ensure accurate glucose results. During the blood draw, you may feel a slight sting, but the procedure is usually quick and simple. The blood sample is then sent to a lab for analysis.

Understanding CMP Results

Your CMP results will include the measured value for each substance along with the normal reference range. These ranges may vary slightly between labs. Abnormal results don't always mean you have a medical condition, as many factors can affect CMP levels, such as medications, diet, and activity level. Your doctor will interpret your results in the context of your overall health and medical history.

Some key points to remember about CMP results:

  • High levels of liver enzymes (ALP, ALT, AST) may indicate liver damage or disease

  • Elevated BUN and creatinine may be signs of kidney dysfunction

  • Abnormal electrolyte levels (sodium, potassium, chloride, carbon dioxide) can affect heart and muscle function

  • High glucose may be a sign of diabetes, while low glucose can cause dizziness and confusion

If you have questions about your CMP results, talk to your doctor. Together you can review the results and discuss any necessary follow-up tests or treatments. Regular CMPs can be an important tool in monitoring your overall health and detecting potential problems early.

To learn more about the CMP and other lab tests, visit Lab Tests Online.