Clotrimazole Dosage Guide: How Much to Take and When (With Chart)

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on December 10th, 2025.

Key Takeaways

  • Clotrimazole is a widely used antifungal medication available in topical and vaginal forms.

  • Dosage varies by form, condition treated, and patient age, with clear guidelines for adults and children.

  • Typical treatment duration ranges from 1 to 4 weeks, depending on the type and severity of the infection.

  • Missed doses should be taken as soon as possible, but avoid doubling up to prevent side effects.

  • Consulting a healthcare provider, especially via telehealth platforms like Doctronic.ai, ensures personalized and safe dosage advice.

Understanding Clotrimazole Uses and Dosages

Clotrimazole is an antifungal medication commonly prescribed to treat fungal infections such as athlete’s foot, ringworm, jock itch, and yeast infections. It works by stopping the growth of fungi, effectively clearing up infections on the skin or mucous membranes. Available in creams, lotions, powders, and vaginal tablets or creams, Clotrimazole’s versatility makes it a go-to treatment for many fungal conditions.

Because fungal infections can vary widely in location and severity, knowing the correct dosage and duration of treatment is essential. Overuse or underuse can lead to ineffective treatment or resistance. This guide breaks down how much Clotrimazole to take, when to take it, and what to do if you miss a dose.

Clotrimazole Dosage Chart

Form

Strength

Typical Adult Dose

Typical Children’s Dose

Frequency

Route

Maximum Daily Dose

Topical Cream/Lotion

1% or 2%

Apply thin layer to affected area 2-3 times daily

Same as adults (consult doctor for children under 2)

2-3 times daily

Topical

As directed, generally no strict max

Vaginal Tablet

100 mg or 200 mg

One 100 mg tablet daily for 6 days or one 200 mg tablet daily for 3 days

Not typically used in children

Once daily

Intravaginal

As directed by healthcare provider

Vaginal Cream

1%

Apply 5 grams intravaginally once daily for 7 days

Not typically used in children

Once daily

Intravaginal

As directed

Clotrimazole Dosage by Condition

Skin Fungal Infections (Athlete’s Foot, Ringworm, Jock Itch)

For these common fungal infections, Clotrimazole cream or lotion is applied directly to the affected area. Adults and children over 2 years typically use a 1% or 2% cream 2 to 3 times daily. The treatment usually lasts for 2 to 4 weeks, even if symptoms improve sooner, to prevent recurrence.

Vaginal Yeast Infections

Clotrimazole vaginal tablets or creams are standard treatments for uncomplicated yeast infections. Adults typically use one 100 mg tablet daily for 6 days or one 200 mg tablet daily for 3 days. Vaginal cream is applied once daily for 7 days. It’s important to complete the full course even if symptoms subside early.

Other Fungal Conditions

For less common fungal infections, dosage and duration can vary. Consulting a healthcare provider is essential to tailor the treatment plan. Telehealth services like Doctronic.ai offer convenient access to doctors who can provide personalized dosing guidance and prescriptions.

What is the Typical Clotrimazole Dose For Adults?

Adults usually apply Clotrimazole topical cream or lotion 2 to 3 times daily on the infected skin area. For vaginal infections, the dose is either a 100 mg tablet once daily for 6 days, a 200 mg tablet once daily for 3 days, or 5 grams of 1% cream once daily for 7 days. Treatment duration depends on the infection type but typically ranges from 1 to 4 weeks.

What is the Typical Clotrimazole Dose For Children?

Children over 2 years can generally use topical Clotrimazole cream or lotion in the same manner as adults for skin infections. However, Clotrimazole is not typically recommended for vaginal use in children. For younger children or special cases, always consult a healthcare provider for safe dosing.

What to Do If You Miss a Dose of Clotrimazole?

If you miss a dose of Clotrimazole, apply it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not double the dose to catch up, as this can increase the risk of side effects. Consistency is key to effective treatment.

How to Adjust Your Clotrimazole Dose For Certain Medical Conditions

Pregnancy and Breastfeeding

Clotrimazole is generally considered safe during pregnancy and breastfeeding when used topically or vaginally, but it’s best to consult a healthcare provider to confirm appropriate dosing and safety.

Severe Liver or Kidney Disease

Since Clotrimazole is minimally absorbed systemically, dose adjustments are rarely necessary. However, if you have severe liver or kidney issues, talk to your doctor before starting treatment.

Clotrimazole Overdose and Warnings

Overdose with topical or vaginal Clotrimazole is rare but may cause increased irritation, redness, or burning at the application site. If you suspect an overdose or experience severe side effects, seek medical attention immediately. Avoid using Clotrimazole on open wounds or broken skin unless directed by a doctor.

Tips For Taking Clotrimazole Safely

  • Follow the full treatment course even if symptoms improve early.

  • Wash your hands before and after applying Clotrimazole.

  • Avoid contact with eyes, nose, or mouth.

  • Use only the prescribed amount and frequency.

  • Store Clotrimazole at room temperature, away from moisture and heat.

Learn More About Clotrimazole Dosage With Doctronic

When it comes to antifungal treatment, personalized advice can make a big difference. Doctronic.ai offers free AI-powered consultations that synthesize the latest medical research to answer your questions quickly. If you need more tailored guidance or prescriptions, Doctronic’s telehealth doctors are available 24/7 across all 50 states, providing convenient, affordable care under $40 per visit.

Doctronic’s AI remembers your health history and preferences, helping you get smarter, faster, and more personal care every time you visit. Whether you’re unsure about Clotrimazole dosage or need a second opinion on your treatment, Doctronic is a trusted resource to turn to.

The Bottom Line About Clotrimazole Dosage

Clotrimazole remains a reliable and effective antifungal medication when used correctly. Understanding the appropriate dosage for your specific condition and following the full treatment course are essential to ensure successful outcomes. If you have any doubts or special health considerations, consulting a healthcare provider is the safest route.

Thanks to advances in telehealth, expert advice is now more accessible than ever. Doctronic.ai combines cutting-edge AI with real doctors to deliver personalized, up-to-date medical guidance right at your fingertips.

Close-up of a hand squeezing ointment from a metal tube onto a fingertip.

Frequently Asked Questions

Clotrimazole is generally not recommended for scalp infections. Other antifungal treatments, like ketoconazole shampoo, are preferred. Consult a healthcare provider for the best option.

Improvement is often seen within a few days, but treatment should continue for the full prescribed duration (usually 1 to 4 weeks) to fully clear the infection.

Topical and vaginal Clotrimazole are generally considered safe during pregnancy, but always check with your healthcare provider before use.

Clotrimazole has minimal systemic absorption, so drug interactions are rare. However, inform your doctor about all medications you are taking to be safe.

If symptoms persist or worsen after the full course, contact a healthcare provider. You can get expert advice quickly through telehealth services like Doctronic.ai.

References

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