Can Ozempic Cause Constipation?

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on November 28th, 2025.

Key Takeaways

  • Semaglutide slows gastric emptying by 50-70% compared to baseline, reducing the speed at which food moves through the digestive tract and leading to harder, less frequent bowel movements.
  • Clinical trials report constipation in 3-7% of patients, making it the third most common GI side effect after nausea (20%) and diarrhea (8-9%).
  • Diabetic patients face compounded risk because diabetic neuropathy already damages enteric nerves controlling bowel function, potentially doubling constipation likelihood.
  • Effective management requires 25-35 grams daily fiber intake, 8+ glasses of water, and 30 minutes of daily walking, which stimulates natural peristalsis and counteracts delayed transit time.
  • Discontinuing treatment isn't recommended since constipation typically resolves within 4-6 weeks as the body adapts, while losing blood sugar benefits (1-2% A1C reduction) poses greater health risks.

Managing Constipation While Taking Ozempic

Ozempic is a popular medication prescribed for type 2 diabetes and weight management. While it offers many benefits, some users experience side effects, including digestive issues. Constipation is one of the concerns patients often ask about. This article explores whether Ozempic can cause constipation, why it might happen, and how to manage it effectively.

Constipation can be an uncomfortable and frustrating experience, especially for those who are already managing other health conditions. When taking Ozempic, it's important to recognize that the medication's primary purpose is to help regulate blood sugar levels in individuals with type 2 diabetes. However, the side effects, including constipation, can sometimes overshadow its benefits. It's crucial for patients to monitor their digestive health closely and communicate any changes to their healthcare provider. By doing so, they can work together to find the best strategies to alleviate these side effects while still effectively managing their diabetes.

In addition to lifestyle changes such as increasing fiber intake and staying active, there are various over-the-counter remedies that can help ease constipation. Fiber supplements, stool softeners, and mild laxatives are commonly used options, but they should be discussed with a healthcare professional before use, particularly for those on medications like Ozempic. Understanding the importance of hydration cannot be overstated; drinking plenty of water can significantly aid in digestion and help prevent constipation. Engaging in regular physical activity can also stimulate bowel movements and promote overall gastrointestinal health, making it an essential part of any management plan.

Woman sitting on a toilet holding her head in pain or distress.What Is Ozempic and How Does It Work?

Understanding Ozempic’s Role

Ozempic is the brand name for semaglutide, a medication used primarily to treat type 2 diabetes. It belongs to a class called GLP-1 receptor agonists, which help regulate blood sugar levels by stimulating insulin secretion and reducing glucagon release. Ozempic slows down gastric emptying, meaning food stays longer in the stomach before moving into the intestines.

Why Slowed Gastric Emptying Matters

This delay in stomach emptying helps control blood sugar spikes after meals and promotes a feeling of fullness, which can aid in weight loss. However, the slower movement of food through the digestive tract can also lead to gastrointestinal side effects, including nausea, bloating, and constipation.

Can Ozempic Cause Constipation?

Constipation as a Side Effect

Yes, constipation is a recognized side effect of Ozempic, although it is less common than nausea or diarrhea. Clinical trials and patient reports indicate that some people experience constipation during their treatment. The frequency varies, but it is significant enough to warrant attention from both patients and healthcare providers.

How Ozempic Leads to Constipation

The primary reason Ozempic can cause constipation is its effect on gastrointestinal motility. By slowing gastric emptying, the medication also slows the transit time of food through the intestines. This slower movement means stool remains longer in the colon, allowing more water to be absorbed, which can harden stool and make bowel movements difficult.

Other Factors That May Increase Constipation Risk

  • Decreased physical activity

  • Low fiber intake

  • Inadequate hydration

  • Concurrent use of other medications that cause constipation

  • Underlying health conditions

Recognizing Constipation Symptoms While on Ozempic

Common Signs to Watch For

Constipation symptoms can vary, but typically include:

  • Infrequent bowel movements (fewer than three per week)

  • Hard, dry stools that are difficult to pass

  • Abdominal discomfort or bloating

  • A sensation of incomplete evacuation

When to Seek Medical Advice

If constipation persists for more than a few days, causes severe pain, or is accompanied by other symptoms like vomiting or rectal bleeding, it is important to consult a healthcare professional. Persistent constipation can lead to complications such as hemorrhoids or fecal impaction.

Managing Constipation While Taking Ozempic

Lifestyle and Dietary Adjustments

Simple changes can often relieve constipation:

  • Increase fiber intake: Foods like fruits, vegetables, whole grains, and legumes add bulk to stool and promote regularity.

  • Stay hydrated: Drinking plenty of water helps soften stool and supports digestive health.

  • Regular exercise: Physical activity stimulates bowel movements and improves overall gut motility.

  • Establish a routine: Try to have bowel movements at the same time each day to train your body.

Over-the-Counter Remedies

If lifestyle changes are not enough, over-the-counter laxatives or stool softeners may be used temporarily. However, these should be taken cautiously and ideally under medical supervision to avoid dependency or worsening symptoms.

Consulting Healthcare Providers via Telehealth

For personalized advice and treatment, telehealth services like Doctronic.ai offer convenient access to licensed doctors. They can evaluate your symptoms, adjust medications if needed, and recommend safe remedies for constipation without requiring an in-person visit.

Balancing Ozempic Benefits and Side Effects

Why Not Stop Ozempic Without Guidance

While constipation can be uncomfortable, it is important not to stop taking Ozempic without consulting a healthcare provider. The medication plays a crucial role in managing blood sugar and supporting weight loss goals, which are vital for long-term health in people with type 2 diabetes.

Working With Your Doctor

Doctors can help balance the benefits of Ozempic with side effect management. Adjustments to dosage, timing, or adding supportive treatments can make a significant difference. Telehealth platforms like Doctronic.ai make it easier to maintain this ongoing communication and care.

Additional Tips for Digestive Health on Ozempic

Monitor Your Body’s Responses

Keep a symptom diary to track bowel habits, diet, fluid intake, and any side effects. This information can help your healthcare provider tailor your treatment plan effectively.

Consider Probiotics

Some people find that probiotics help maintain gut health and regularity. Discuss with your doctor whether a probiotic supplement might be beneficial in your case.

Avoid Other Constipating Medications When Possible

If you are on multiple medications, ask your provider if any could be contributing to constipation. Alternative options might be available.

Finding Support and Reliable Information

Why Use Trusted Telehealth Services

When dealing with medication side effects like constipation, quick access to expert advice is essential. Doctronic.ai provides AI-powered and doctor-backed telehealth visits that are affordable and available 24/7 across all 50 states. This service offers a modern approach to primary care, combining the latest medical research with personalized patient care.

How Doctronic.ai Enhances Your Care

Doctronic’s AI doctor remembers your medical history and provides answers based on up-to-date, peer-reviewed research. This helps you get accurate information about side effects, treatment options, and when to seek further care. Using Doctronic.ai can reduce anxiety and improve health outcomes by making quality care accessible anytime.

Smiling female doctor in a white coat with arms crossed.Understanding Constipation in the Context of Diabetes

Why People with Diabetes May Experience Constipation

Diabetes itself can affect the nerves that control the digestive system, a condition called diabetic neuropathy. This can slow down bowel movements and contribute to constipation. When combined with medications like Ozempic that slow gastric emptying, the risk increases.

Importance of Holistic Management

Managing diabetes effectively with the right medications, diet, and lifestyle is key to reducing digestive complications. Regular check-ins with healthcare providers, including through telehealth platforms, help ensure all aspects of health are addressed.

Taking Control of Your Health with Ozempic

Ozempic offers significant benefits for managing type 2 diabetes and supporting weight loss, but like any medication, it can cause side effects such as constipation. Understanding why constipation happens and knowing how to manage it can make your treatment experience smoother. Lifestyle changes, medical advice, and Doctronic.ai provide the support needed to stay on track with your health goals while minimizing discomfort.

Frequently Asked Questions

Constipation is a known but less common side effect compared to nausea or diarrhea. It varies by individual.

For many, constipation improves as the body adjusts to the medication over a few weeks. Persistent symptoms should be evaluated by a doctor.

Occasional use of laxatives may be safe, but it is best to consult your healthcare provider before starting any new medication.

Do not stop Ozempic without medical advice. Your doctor can help manage side effects while maintaining treatment benefits.

Telehealth services like Doctronic.ai offer fast, affordable consultations with doctors who can provide guidance and treatment options.

References 

The Bottom Line

Most patients experience mild, temporary constipation that improves with increased fiber, hydration, and exercise within the first month of treatment. The digestive side effects rarely outweigh the significant metabolic benefits of continued therapy. If you're experiencing persistent symptoms or have concerns about starting treatment, Doctronic can provide personalized guidance.

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