Avanafil Dosage Guide: How Much to Take and When (With Chart)

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on December 8th, 2025.

Key Takeaways

  • Avanafil is a prescription medication used to treat erectile dysfunction (ED).

  • Typical adult doses range from 50 mg to 200 mg taken about 15 to 30 minutes before sexual activity.

  • The maximum recommended dose is 200 mg per day; do not exceed this without medical advice.

  • Dosage adjustments may be necessary for certain medical conditions or when taking interacting medications.

  • Children and adolescents are not typically prescribed Avanafil.

  • If you miss a dose, take it as soon as possible, but do not double-dose within 24 hours.

  • Consult a healthcare professional for personalized dosage guidance; telehealth services like Doctronic.ai offer convenient access to expert advice.

Understanding Avanafil Uses and Dosages

Avanafil is a fast-acting medication designed to help men with erectile dysfunction achieve and maintain an erection suitable for sexual activity. Knowing the correct dosage and timing is essential to maximize effectiveness while minimizing side effects. This guide breaks down the typical dosages, how to take Avanafil safely, and what to do if you need personalized advice.

Avanafil Dosage Chart

Form

Strength

Typical Adult Dose

Typical Children’s Dose

Frequency

Route

Maximum Daily Dose

Tablet

50 mg

50 mg to 100 mg

Not recommended

Once daily, as needed

Oral

200 mg

Tablet

100 mg

50 mg to 100 mg

Not recommended

Once daily, as needed

Oral

200 mg

Tablet

200 mg

Up to 200 mg

Not recommended

Once daily, as needed

Oral

200 mg

Avanafil Dosage by Condition

Erectile Dysfunction (ED)

Avanafil is primarily prescribed for erectile dysfunction. The typical dosing starts at 100 mg taken 15 to 30 minutes before sexual activity. Based on response and tolerability, the dose may be decreased to 50 mg or increased to a maximum of 200 mg.

Dosage Adjustments for Medical Conditions

Certain health conditions and medications can impact how Avanafil should be dosed. For example, men with moderate liver impairment or severe kidney impairment may require dose adjustments. It is critical to discuss your full medical history with a healthcare provider before starting Avanafil.

What Is the Typical Avanafil Dose for Adults?

For most adult men, the starting dose of Avanafil is 100 mg taken orally approximately 15 to 30 minutes before anticipated sexual activity. Depending on how well the medication is tolerated and its effectiveness, the dose can be adjusted. Some men may find 50 mg sufficient, while others may require up to 200 mg. However, it is important not to exceed 200 mg in a 24-hour period.

How to Take Avanafil

Avanafil tablets should be swallowed whole with water. It can be taken with or without food, but a high-fat meal may delay its onset of action. The medication is designed for use on an as-needed basis rather than daily use, so it should be taken only before sexual activity.

What Is the Typical Avanafil Dose for Children?

Avanafil is not approved for use in children or adolescents under 18 years of age. Its safety and effectiveness have not been established in this population, so it should only be used by adults with a prescription from a healthcare provider.

What to Do If You Miss a Dose of Avanafil?

Since Avanafil is taken as needed rather than on a fixed schedule, missing a dose is generally not a concern. If you forget to take it before sexual activity, simply take the medication before the next planned encounter. Do not double up doses within 24 hours to avoid potential side effects.

How to Adjust Your Avanafil Dose for Certain Medical Conditions

Liver Impairment Adjustment

For patients with moderate liver impairment, starting at a lower dose such as 50 mg is recommended. Close monitoring is necessary to avoid accumulation and increased side effects.

Kidney Impairment Adjustment

In severe kidney impairment, dose adjustments or alternative treatments may be needed. Mild to moderate kidney issues usually do not require dosage changes.

Avanafil Overdose and Warnings

Taking more than the recommended maximum dose of 200 mg per day can increase the risk of serious side effects such as prolonged erections (priapism), sudden vision loss, or hearing loss. If an overdose is suspected, seek emergency medical attention immediately.

Do not use Avanafil if you are taking nitrates or have certain cardiovascular conditions without consulting a healthcare professional.

Tips for Taking Avanafil Safely

  • Always follow your healthcare provider’s dosing instructions.

  • Inform your doctor about all medications and supplements you are taking.

  • Avoid excessive alcohol consumption when using Avanafil.

  • Do not use Avanafil with other ED medications.

  • Report any unusual side effects or prolonged erections to your doctor immediately.

Learn More About Avanafil Dosage With Doctronic

Personalized advice about Avanafil dosage can make a big difference in treatment success and safety. Doctronic.ai provides quick, AI-powered doctor visits that combine the latest medical research with personalized care. You can get answers to your dosage questions and connect with licensed healthcare providers for telehealth video visits anytime, anywhere in the US, all for an affordable price under $40.

Doctronic’s AI doctor remembers your history and tailors recommendations just for you, making it easier to manage your ED treatment effectively. Whether you want a second opinion or need help adjusting your dose, Doctronic is a convenient and trusted option.

The Bottom Line About Avanafil Dosages

Choosing the right Avanafil dose involves balancing effectiveness with safety. Starting at a moderate dose and adjusting based on your response is key. Avoid exceeding the maximum dose and always seek professional advice if you have underlying health issues or take other medications. Telehealth services like Doctronic.ai make it easier than ever to get expert guidance without leaving home.

A small pile of round red tablets

Frequently Asked Questions

Avanafil is intended for use as needed before sexual activity, not for daily use. Taking it daily is not recommended without medical supervision.

Take Avanafil about 15 to 30 minutes before sexual activity for best results.

Sometimes it takes a few tries to find the right dose. Consult your healthcare provider or use telehealth services like Doctronic.ai to discuss dose adjustments.

Some medications can interact with Avanafil, especially nitrates and certain blood pressure drugs. Always inform your doctor of all medications you take.

No, Avanafil is not approved for use in women or children.

Common side effects include headache, flushing, nasal congestion, and dizziness. Serious side effects require immediate medical attention.

References

Related Articles