Advair vs. Symbicort: How These Popular Asthma and COPD Inhalers Compare

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on December 15th, 2025.

Key takeaways

  • Advair and Symbicort are widely prescribed inhalers for asthma and COPD management, each combining a corticosteroid and a long-acting bronchodilator.

  • Understanding their differences in active ingredients, usage, and side effects helps patients and caregivers make informed treatment choices.

  • Both inhalers require a prescription and proper guidance, which can be conveniently accessed through telehealth services like Doctronic.ai.

  • Choosing the right inhaler depends on individual health needs, response to medication, and doctor recommendations.

  • Regular follow-ups and monitoring are essential for effective asthma and COPD management, with AI-powered telehealth offering personalized support.

Understanding Advair and Symbicort: What Are They?

Advair and Symbicort are two of the most common inhalers prescribed for people living with asthma or chronic obstructive pulmonary disease (COPD). Both medications combine two types of drugs: a corticosteroid to reduce inflammation and a long-acting bronchodilator to keep airways open. Despite these similarities, they differ in their specific ingredients, delivery mechanisms, and recommended uses.

Knowing how each inhaler works and what sets them apart can help patients manage their respiratory conditions more effectively. This article breaks down the key features of Advair and Symbicort to guide you in understanding which might be better suited for your health needs.

Advair contains fluticasone propionate, a potent corticosteroid that helps to decrease inflammation in the lungs, and salmeterol, a long-acting beta-agonist that relaxes the muscles around the airways, making breathing easier. It is often prescribed for patients who require regular maintenance therapy to control their asthma or COPD symptoms. The inhaler is designed for twice-daily use, ensuring a consistent level of medication in the body, which can be crucial for preventing exacerbations and maintaining overall lung function.

On the other hand, Symbicort combines budesonide, another corticosteroid, with formoterol, a long-acting bronchodilator. One of the notable features of Symbicort is its versatility; it can be used as both a maintenance treatment and a rescue inhaler for acute asthma symptoms. This dual functionality may appeal to patients who experience sudden breathing difficulties, as it offers immediate relief while also addressing long-term control. Symbicort is typically taken twice daily as well, but its formulation allows for flexibility in managing symptoms as they arise.

Active Ingredients and How They Work

Advair: Fluticasone and Salmeterol

Advair combines fluticasone propionate, a corticosteroid, with salmeterol, a long-acting beta2-agonist (LABA). Fluticasone reduces airway inflammation, which is a major cause of asthma and COPD symptoms. Salmeterol helps relax the muscles around the airways, making breathing easier by keeping the airways open for up to 12 hours.

This combination helps control symptoms like wheezing, shortness of breath, and coughing, and it works best when used regularly as prescribed, not just during flare-ups.

Symbicort: Budesonide and Formoterol

Symbicort contains budesonide, another corticosteroid, paired with formoterol, a LABA with a faster onset of action compared to salmeterol. Budesonide also reduces inflammation, while formoterol opens the airways quickly and maintains that effect for up to 12 hours.

Because formoterol acts faster, Symbicort can sometimes be used for both maintenance and quick relief, depending on your doctor’s instructions. This dual role is a notable difference from Advair.

Usage and Dosage Differences

How to Use Advair

Advair is typically prescribed as a maintenance inhaler, meaning it should be used twice daily to keep symptoms under control. It is not intended for immediate relief of sudden asthma attacks. Patients should use it consistently, even when feeling well, to prevent flare-ups.

How to Use Symbicort

Symbicort is also used twice daily for maintenance, but it has the added flexibility of being used as a quick-relief inhaler in some cases. This means patients might use it to manage sudden symptoms, but only under a doctor’s guidance.

Both inhalers require proper inhalation technique to ensure the medication reaches the lungs effectively. Patients should follow their healthcare provider’s instructions carefully and consult them if unsure about usage.

Woman using a blue asthma inhaler.Side Effects and Safety Considerations

Common Side Effects

  • Thrush (oral yeast infection)

  • Hoarseness or voice changes

  • Headache

  • Tremors or nervousness

  • Increased heart rate

Both Advair and Symbicort share similar side effects due to their corticosteroid and LABA components. Rinsing the mouth after inhalation can help reduce the risk of thrush.

Warnings and Precautions

Long-acting beta2-agonists, like salmeterol and formoterol, carry a warning about increased risk of asthma-related death if used improperly. They should always be used with a corticosteroid and never as standalone quick-relief inhalers unless specifically advised by a doctor.

Patients with heart conditions, high blood pressure, or certain other illnesses should discuss their medical history with their healthcare provider before starting either medication.

Which Inhaler Is Right for You?

Factors to Consider

  • Symptom control needs: If quick relief is important, Symbicort’s faster-acting formoterol may be advantageous.

  • Doctor’s recommendation: Your healthcare provider will consider your medical history, the severity of symptoms, and your response to previous treatments.

  • Insurance coverage and cost: These can vary, so checking your plan’s formulary is helpful.

  • Ease of use: Some patients prefer one inhaler device over another based on comfort and convenience.

Consulting with Healthcare Providers via Telehealth

Getting the right inhaler and dosage requires a thorough evaluation by a healthcare professional. Telehealth platforms like Doctronic.ai offer easy access to licensed doctors who can assess your symptoms, review your medical history, and prescribe medications remotely. This service is available 24/7 across all 50 states, providing affordable and convenient care without waiting rooms.

Doctronic’s AI-powered system also delivers personalized health insights and recommendations, making it easier to manage chronic respiratory conditions with confidence.

Tips for Managing Asthma and COPD with Inhalers

Proper Inhaler Technique

Effective treatment depends on using your inhaler correctly. Common steps include shaking the inhaler, exhaling fully before inhaling the medication, and holding your breath for a few seconds after inhalation. Ask your doctor or pharmacist for a demonstration or use online resources to master the technique.

Regular Monitoring and Follow-Up

Asthma and COPD symptoms can change over time. Regular check-ins with your healthcare provider help adjust treatment plans as needed. Using telehealth services like Doctronic.ai makes these follow-ups easier, especially for those with busy schedules or limited mobility.

Lifestyle and Environmental Factors

Avoiding triggers such as smoke, allergens, and pollution complements medication use. Maintaining a healthy lifestyle with exercise and nutrition also supports lung health.

Choosing the Best Support for Your Respiratory Health

Managing asthma or COPD involves more than just picking the right inhaler. It requires ongoing care, education, and access to healthcare professionals who understand your unique needs. Doctronic.ai provides a modern approach to healthcare by combining AI-driven insights with real doctor consultations. This makes it easier to get timely advice, prescription refills, and personalized treatment plans without leaving home.

Whether you are starting treatment or adjusting your current regimen, having reliable support can make a significant difference in your quality of life.

Frequently Asked Questions

Switching inhalers should only be done under medical supervision. Your doctor will determine the best option based on your symptoms and treatment goals.

Both Advair and Symbicort have pediatric formulations but require careful dosing and monitoring by a healthcare provider.

Take the missed dose as soon as you remember, unless it is near the time for your next dose. Do not double up doses. Contact your doctor if unsure.

Discuss with your healthcare provider before using any medication during pregnancy. They will weigh the benefits and risks to ensure safety for you and your baby.

Improved breathing, fewer symptoms, and reduced need for rescue inhalers are signs your inhaler is effective. Report any worsening symptoms to your doctor promptly.

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