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What Risks Come with Intralesional Corticosteroid Injections?
Published: Dec 17, 2023
While intralesional corticosteroid injections are generally safe, they come with potential risks. Let's examine the factors that could affect your treatment.
Local Adverse Effects
Common local side effects include skin atrophy and hypopigmentation, especially if the drug is injected too deeply. These effects are usually temporary but can sometimes be permanent, particularly in individuals with darker skin tones.
Systemic Side Effects
Although rare, systemic side effects like hyperglycemia and Cushing syndrome can occur. These are more likely with high cumulative doses, emphasizing the importance of careful dosing and monitoring.
Avoiding Injection Pitfalls
To minimize risks, it's crucial to avoid injecting into the subcutaneous layer and to use the lowest effective dose. Understanding facial anatomy is essential to prevent accidental intravascular injections, which can lead to severe complications.
Frequently Asked Questions
Skin atrophy and hypopigmentation are common.
No, they are rare but can occur with high doses.
Use the lowest effective dose and avoid subcutaneous injection.
The Bottom Line
Are you aware of the risks associated with your treatment?
References
- Richards RN. Update on intralesional steroid: focus on dermatoses. J Cutan Med Surg 2010; 14:19.
- Sukhumthammarat W, Putthapiban P, Sriphrapradang C. Local Injection of Triamcinolone Acetonide: A Forgotten Aetiology of Cushing's Syndrome. J Clin Diagn Res 2017; 11:OR01.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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