The Hidden Risks of Isotretinoin: What You Should Know!
Published: Dec 19, 2023

Medically reviewed by Oghenefejiro Okifo | MD, Harvard Medical School | Henry Ford Hospital - Detroit, MI on December 19th, 2023.
Isotretinoin is a game-changer for acne, but it's important to understand its risks. Here's what you need to be aware of before considering this treatment.
Contents
Understanding the Side Effects
Isotretinoin can lead to several side effects ranging from dry skin and lips to more serious concerns like birth defects if taken during pregnancy. It's also linked to mood changes, which require careful monitoring.
The Pregnancy Dilemma
As a teratogenic drug, isotretinoin can cause serious birth defects. Women of childbearing potential must use effective contraception and participate in monitoring programs like iPLEDGE to prevent pregnancy during treatment.

Isotretinoin and Your Mental Health
Though not conclusively proven, isotretinoin has been associated with depression and suicidal thoughts. It's crucial for patients to be aware of these potential effects and communicate any mood changes to their healthcare provider.
Frequently Asked Questions
Dry skin, birth defects, mood changes.
Yes, it's highly teratogenic.
It may be, so monitoring is essential.
Key Takeaways
Isotretinoin can be beneficial, but its risks must be handled with care.
Want to know more about isotretinoin's risks? Chat with Doctronic for insights!Related Articles
References
Mathers WD, et al. Cornea 1991; 10:286.
Neudorfer M, et al. Arch Dermatol 2012; 148:803.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.