Are Topical Medications the Key to Healing Anal Fissures?
Are Topical Medications the Key to Healing Anal Fissures?
Why It Matters
Topical medications offer a non-invasive way to treat anal fissures effectively. Learn about the different options and how they work.
Contents
- Topical Nifedipine
- Topical Nitroglycerin
Topical Nifedipine
Nifedipine is a topical vasodilator that helps heal anal fissures by relaxing the anal sphincter. Applied as a 0.2 to 0.3% ointment, it increases blood flow and reduces sphincter pressure. Nifedipine is a preferred choice due to its lower risk of side effects compared to other treatments.
Topical Nitroglycerin
Nitroglycerin ointment is another effective treatment that works similarly to nifedipine by increasing blood flow. Available as a 0.4% commercially prepared ointment, it is applied twice daily. While effective, it may cause headaches and should be used cautiously if taken with certain medications.
FAQs
What does nifedipine do?
It relaxes the anal sphincter and increases blood flow to promote healing.
How is nitroglycerin used?
It's applied as a 0.4% ointment twice daily to aid fissure healing.
Are there side effects of nitroglycerin?
Yes, headaches are common, and interactions with some drugs are possible.
Key Takeaways
Topical medications are a promising non-invasive option for treating anal fissures.
Additional References
- Ezri T, Susmallian S. Topical nifedipine vs. topical glyceryl trinitrate for treatment of chronic anal fissure. Dis Colon Rectum 2003; 46:805.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.