What's Causing Your Persistent Itch?
Published: Jan 13, 2024
Pruritus, or the sensation of itching, is more than just an annoying feeling. It can be a sign of various underlying conditions, from skin disorders to systemic diseases.
Contents
Understanding Pruritus
Pruritus is a symptom rather than a disease, often linked with skin conditions like eczema or psoriasis. However, it can also be a sign of illnesses affecting other body systems, leading to complex diagnostic challenges for healthcare providers.
Why Do We Itch?
The sensation of itch is transmitted through specific nerve fibers in the skin that send signals to the brain. These signals can be triggered by various substances, including histamines and other chemicals involved in the body's immune response.

Who is Most at Risk?
Older adults frequently experience pruritus due to dry skin or age-related changes in nerve fibers. Women may face specific types of itch related to hormonal changes, while certain systemic diseases like kidney or liver disorders can also lead to persistent itching.
Frequently Asked Questions
Common causes include dermatologic conditions, systemic diseases, and neuropathic disorders.
Yes, pruritus can indicate systemic issues like kidney or liver disease.
Pruritus is more common in older adults and can vary by gender and ethnicity.
Wrapping Up
Understanding the underlying cause of pruritus is crucial for effective treatment.
References
- Ständer S, Schäfer I, Phan NQ, et al. Prevalence of chronic pruritus in Germany: results of a cross-sectional study in a sample working population of 11,730. Dermatology 2010; 221:229.
- Valdes-Rodriguez R, Mollanazar NK, González-Muro J, et al. Itch prevalence and characteristics in a Hispanic geriatric population: a comprehensive study using a standardized itch questionnaire. Acta Derm Venereol 2015; 95:417.
- Berger TG, Shive M, Harper GM. Pruritus in the older patient: a clinical review. JAMA 2013; 310:2443.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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