Symptoms of HIT: What to Look For
Symptoms of HIT: What to Look For
Spot the Signs
Heparin-induced thrombocytopenia (HIT) can be a silent threat with serious consequences. Learn about the symptoms to watch for in this condition.
Contents
- Thrombocytopenia
- Thrombosis
- Skin Reactions
Thrombocytopenia
The hallmark of HIT is a significant drop in platelet count, often seen 5 to 10 days after starting heparin. This drop can lead to symptoms like unusual bruising or bleeding. Monitoring platelet levels is vital for early detection and intervention.
Thrombosis
HIT can lead to dangerous blood clots in veins or arteries, known as thrombosis. Symptoms may include swelling, pain in the limbs, or sudden shortness of breath if pulmonary embolism occurs. These signs require immediate medical attention.

Skin Reactions
Some people experience skin reactions like redness or necrosis at heparin injection sites. Although less common, these symptoms can be an early warning sign of HIT. Recognizing these symptoms can prevent further complications.
FAQs
What is thrombocytopenia?
It's a drop in platelet count, a key symptom of HIT.
What are thrombosis symptoms?
Symptoms include limb pain, swelling, or shortness of breath.
Can skin reactions indicate HIT?
Yes, skin reactions at injection sites can be an early sign.
Recognizing Symptoms
Recognizing HIT symptoms early is crucial for preventing serious complications.
Additional References
- Warkentin TE. Clinical presentation of heparin-induced thrombocytopenia. Semin Hematol 1998; 35:9.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.