Spotlight on Symptoms: Is Your Body Telling You About Adrenal Insufficiency?
Published: Sep 30, 2023
Recognizing the symptoms of adrenal insufficiency early can prevent potential crises. Let's explore the telltale signs your body might be trying to show you.
Common Symptoms
Adrenal insufficiency often starts with subtle signs like fatigue, unexplained weight loss, and changes in appetite. You might also experience muscle weakness or joint pain. These nonspecific symptoms can easily be mistaken for other conditions, delaying diagnosis.
Skin Changes
A unique symptom of primary adrenal insufficiency is hyperpigmentation, where skin darkens in areas exposed to friction or pressure. This occurs due to increased hormone production trying to compensate for lack of adrenal hormones. Often, these changes happen gradually, making them easy to overlook.

Digestive Issues
Digestive problems like nausea, vomiting, or abdominal pain can also signal adrenal insufficiency. These symptoms might worsen during stress or illness, potentially leading to an adrenal crisis. Awareness and prompt treatment are key to managing these digestive disturbances.
Frequently Asked Questions
Fatigue, weight loss, and muscle weakness are common early symptoms.
Skin may darken in areas exposed to friction or pressure.
Yes, nausea and abdominal pain can indicate adrenal insufficiency.
Yes, symptoms are nonspecific and can be confused with other illnesses.
The Bottom Line
Being aware of adrenal insufficiency symptoms can lead to earlier diagnosis and better health outcomes.
References
- Erichsen MM, LΓΈvΓ₯s K, Skinningsrud B, et al. Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: observations from a Norwegian registry. J Clin Endocrinol Metab 2009; 94:4882.
- Mitchell AL, Pearce SH. Autoimmune Addison disease: pathophysiology and genetic complexity. Nat Rev Endocrinol 2012; 8:306.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
15-min consultation. No hidden costs.
AI Doctor Visit Required
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?