Recognizing the Signs: Symptoms of Polycythemia Vera
Published: Oct 08, 2023
Polycythemia vera (PV) can cause a variety of symptoms, some subtle and others more noticeable. Knowing what to look for can help you seek medical attention early.
Contents
Itchy Skin: The Telltale Sign
One of the most common and distinctive symptoms of PV is itchy skin, especially after a warm bath or shower. This isn't your ordinary itch - it can be intense and widespread. It's like your skin is trying to send you a message that something's not quite right inside your body.
Fatigue and Dizziness: The Energy Drain
Many people with PV experience fatigue and dizziness. This happens because your blood becomes thicker due to the excess red blood cells, making it harder for your heart to pump blood effectively. It's like trying to push thick syrup through a straw - it takes more effort and doesn't flow as easily.

Headaches and Vision Problems: The Head Game
Headaches are common in PV, and some people experience blurred vision or blind spots. These symptoms occur because the thickened blood can affect circulation to your brain and eyes. Think of it as a traffic jam in your blood vessels, slowing down the flow to important areas.
Enlarged Spleen: The Hidden Symptom
An enlarged spleen is a common feature of PV, though you might not notice it yourself. It can cause a feeling of fullness or pain in the upper left part of your abdomen. Your spleen works overtime in PV, trying to filter out the excess blood cells. It's like a overworked vacuum cleaner that's gotten too full.
Frequently Asked Questions
No, these symptoms can have many causes.
Symptoms often develop slowly over time.
Yes, some people with PV have no noticeable symptoms.
Symptoms can vary widely between individuals.
Yes, PV symptoms may fluctuate over time.
When to Seek Help
If you're experiencing persistent symptoms like those described, it's important to consult with a healthcare provider.
References
- Tefferi A, Barbui T. Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management. Am J Hematol. 2020;95(12):1599-1613.
- Mesa RA, Niblack J, Wadleigh M, et al. The burden of fatigue and quality of life in myeloproliferative disorders (MPDs): an international Internet-based survey of 1179 MPD patients. Cancer. 2007;109(1):68-76.
- Geyer H, Scherber R, Kosiorek H, et al. Symptomatic Profiles of Patients With Polycythemia Vera: Implications of Inadequately Controlled Disease. J Clin Oncol. 2016;34(2):151-159.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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