Contents
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Initial Evaluations
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Advanced Diagnostic Techniques
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Challenges in Diagnosis
How is Fever of Unknown Origin Diagnosed?
How is Fever of Unknown Origin Diagnosed?
Why It Matters
Diagnosing fever of unknown origin (FUO) can be complex, involving multiple tests and evaluations. Let's explore the diagnostic process.
Contents
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Initial Evaluations
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Advanced Diagnostic Techniques
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Challenges in Diagnosis
Initial Evaluations
When a patient presents with FUO, initial evaluations include a thorough medical history, physical examination, and basic lab tests. These steps aim to identify any obvious causes and rule out common conditions. Despite these efforts, many FUO cases remain undiagnosed, necessitating further investigation.
Advanced Diagnostic Techniques
When initial tests are inconclusive, more advanced diagnostics come into play. Imaging techniques like CT scans and MRI can help identify hidden infections or tumors. Specialized tests, such as tissue biopsies, may be required to confirm conditions like tuberculosis or malignancies.
Challenges in Diagnosis
Diagnosing FUO is challenging due to the nonspecific nature of fever and the wide range of potential causes. Some cases resolve without a diagnosis, while others might require repeat testing. The lack of clear symptoms in many diseases adds to the complexity.
FAQs
What tests are used for FUO?
Initial tests include medical history, physical exam, and basic lab tests.
What if initial tests are inconclusive?
Advanced diagnostics like imaging and biopsies are used.
Why is diagnosing FUO challenging?
The nonspecific nature of fever and diverse causes make it complex.
Can FUO resolve on its own?
Yes, some cases may resolve without a diagnosis.
The Bottom Line
Diagnosing FUO requires persistence and a comprehensive approach.
Additional References
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Cunha BA, Lortholary O, Cunha CB. Fever of unknown origin: a clinical approach. Am J Med 2015; 128:1138.e1.
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Fusco FM, Pisapia R, Nardiello S, et al. Fever of unknown origin (FUO): which are the factors influencing the final diagnosis? A 2005-2015 systematic review. BMC Infect Dis 2019; 19:653.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.