Contents
How is Fever of Unknown Origin Diagnosed?
Published: Jun 28, 2024
Diagnosing fever of unknown origin (FUO) can be complex, involving multiple tests and evaluations. Let's explore the diagnostic process.
Initial Evaluations
When a patient presents with FUO, initial evaluations include a thorough medical history, physical examination, and basic lab tests. These steps aim to identify any obvious causes and rule out common conditions. Despite these efforts, many FUO cases remain undiagnosed, necessitating further investigation.
Advanced Diagnostic Techniques
When initial tests are inconclusive, more advanced diagnostics come into play. Imaging techniques like CT scans and MRI can help identify hidden infections or tumors. Specialized tests, such as tissue biopsies, may be required to confirm conditions like tuberculosis or malignancies.
Challenges in Diagnosis
Diagnosing FUO is challenging due to the nonspecific nature of fever and the wide range of potential causes. Some cases resolve without a diagnosis, while others might require repeat testing. The lack of clear symptoms in many diseases adds to the complexity.
Frequently Asked Questions
Initial tests include medical history, physical exam, and basic lab tests.
Advanced diagnostics like imaging and biopsies are used.
The nonspecific nature of fever and diverse causes make it complex.
Yes, some cases may resolve without a diagnosis.
The Bottom Line
Diagnosing FUO requires persistence and a comprehensive approach.
References
- Cunha BA, Lortholary O, Cunha CB. Fever of unknown origin: a clinical approach. Am J Med 2015; 128:1138.e1.
- Fusco FM, Pisapia R, Nardiello S, et al. Fever of unknown origin (FUO): which are the factors influencing the final diagnosis? A 2005-2015 systematic review. BMC Infect Dis 2019; 19:653.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
Top licensed doctors
Available in all 50 states
Full service care
Prescriptions, referrals & treatment
No insurance needed
All notes available in Doctronic
15-min consultation. No hidden costs.
AI Doctor Visit Required
Please Chat With Our AI Doctor First
Our AI doctor assessment helps our human doctors prepare for your video visit and provide better care
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?