Contents
What's the Mystery Behind Primary Amenorrhea?
Published: Jan 14, 2024
Primary amenorrhea, the absence of menstruation by age 15, can be puzzling. This article explores common causes and what they mean for young women.
Understanding Primary Amenorrhea
Primary amenorrhea is when a girl hasn't started menstruating by age 15. It's important to evaluate this condition to find the underlying cause. It can result from issues in the hypothalamus, pituitary, ovaries, uterus, or vagina.
Genetic and Anatomical Causes
A significant cause of primary amenorrhea is genetic or anatomical abnormalities. Gonadal dysgenesis, including Turner syndrome, is the most common, affecting 43% of cases. Other causes can include Müllerian agenesis and congenital defects in reproductive organs.
Hormonal Factors and Delays
Hormonal issues can also lead to primary amenorrhea. Conditions like functional hypothalamic amenorrhea, where stress or weight loss affects hormone release, are common. Some cases involve delayed puberty, seen more often in boys but can occur in girls.
Frequently Asked Questions
It's the absence of menstruation by age 15.
Genetic issues or hormonal imbalances are common causes.
Turner syndrome affects 43% of primary amenorrhea cases.
Yes, stress can disrupt hormone release leading to amenorrhea.
Yes, it can occur but is less common in females.
The Bottom Line
Understanding the causes of primary amenorrhea is crucial for proper diagnosis and treatment.
References
- Practice Committee of the American Society for Reproductive Medicine. Fertil Steril 2006; 86:S148.
- Reindollar RH, Byrd JR, McDonough PG. Am J Obstet Gynecol 1981; 140:371.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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