How Do You Test for Genital Herpes? Find Out Now!
Published: Aug 25, 2024
If you suspect you have genital herpes, testing is the key to a clear diagnosis. Here's what you need to know about the testing process.
Contents
PCR Testing: The Gold Standard
Polymerase chain reaction (PCR) testing is currently the most accurate method for diagnosing genital herpes. It involves taking a sample from a sore and detecting the virus's DNA. PCR is favored for its sensitivity and can distinguish between HSV-1 and HSV-2.
Viral Cultures: An Alternative Method
Viral culture tests involve growing the virus from a sample taken from an active lesion. While effective, the sensitivity is lower compared to PCR, especially as sores begin to heal. Cultures are usually processed within five days, providing a timely diagnosis.

Serologic Tests: Detecting Past Infections
Serologic tests identify antibodies to HSV in the blood. They are useful for identifying past infections, even without current symptoms. However, these tests cannot determine the location of an infection, whether oral or genital.
Frequently Asked Questions
PCR testing is the most accurate for diagnosing herpes.
They grow the virus from lesions to diagnose herpes.
Yes, they identify HSV antibodies in the blood.
Key Takeaways
Timely and accurate testing is vital for managing genital herpes.
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References
Kimberlin DW, Lakeman FD, Arvin AM, et al. Application of the polymerase chain reaction to the diagnosis and management of neonatal herpes simplex virus disease. J Infect Dis 1996; 174:1162.
Schacker T, Zeh J, Hu HL, et al. Frequency of symptomatic and asymptomatic herpes simplex virus type 2 reactivations among human immunodeficiency virus-infected men. J Infect Dis 1998; 178:1616.
Always discuss health information with your healthcare provider.