Why Does My Stomach Hurt After Taking Ibuprofen?
Ibuprofen can irritate your stomach lining and reduce protective mucus production. This nonsteroidal anti-inflammatory drug (NSAID) blocks enzymes called COX-1 and COX-2, which normally help maintain the stomach's protective barrier. Without adequate protection, stomach acid can damage the lining, causing pain, inflammation, or ulcers. Studies show that 10-20% of regular NSAID users develop stomach problems. Taking ibuprofen with food, using the lowest effective dose, or switching to enteric-coated versions can reduce irritation. If stomach pain persists or you experience nausea, vomiting, or black stools, stop taking ibuprofen and consult a healthcare provider immediately.
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