What Medications Should You Not Take with Grapefruit?

Over 85 medications interact dangerously with grapefruit, including many common prescriptions. Grapefruit contains compounds called furanocoumarins that block intestinal enzymes responsible for breaking down certain drugs. This leads to higher blood levels and increased risk of serious side effects. Major categories include cholesterol-lowering statins like atorvastatin, blood pressure medications such as felodipine, anti-anxiety drugs like buspirone, and immunosuppressants including cyclosporine. Heart rhythm medications, some antidepressants, and certain cancer treatments also interact with grapefruit. The effect can last up to 72 hours after consuming grapefruit juice.

Related Questions

• How long after taking medication can I eat grapefruit?

• Does white grapefruit interact with medications differently than pink?

• What other citrus fruits interact with prescription drugs?

• Can grapefruit supplements cause the same drug interactions?

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