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Understanding GLP-1 Side Effects
February 19th, 2026

What is Ozempic Face

Ozempic face refers to facial volume loss that can occur during rapid weight loss with GLP-1 medications like Ozempic. This aesthetic side effect happens when facial fat pads shrink faster than skin can tighten, creating a gaunt or aged appearance. Studies show this occurs in approximately 15-20% of patients who lose significant weight quickly. The effect is more pronounced in patients over 40 and those losing more than 10% of their body weight within 6 months. Gradual weight loss approaches and proper hydration may help minimize these facial changes while maintaining health benefits.

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