Why Does Eczema Itch So Much?
Published: Dec 24, 2023
Eczema's persistent itch can be maddening, but understanding the cause can help you find relief.
Contents
The Science of Itch
Eczema itch is more than skin deep; it's a complex interaction between the skin and the nervous system. Inflammation from eczema causes the release of itch-inducing chemicals, triggering nerve fibers in the skin to send itch signals to the brain.
The Role of Cytokines
Cytokines, proteins involved in inflammation, play a significant role in eczema itch. They disrupt normal skin function and increase itchiness by interacting with nerve fibers. Treatments targeting cytokines can help alleviate the itch.

Managing the Itch
Managing eczema itch involves a combination of skincare and medical treatments. Moisturizers and antihistamines can soothe the skin, while topical steroids and other medications help reduce inflammation and itchiness.
Frequently Asked Questions
Inflammation releases chemicals that trigger itch signals.
Proteins that mediate inflammation and contribute to itch.
Through skincare, moisturizers, and medical treatments.
Yes, they can reduce itchiness in eczema.
Key Takeaways
Understanding the itch's root cause is essential for effective eczema management.
References
- Yosipovitch G, Berger T, Fassett MS. Neuroimmune interactions in chronic itch of atopic dermatitis. J Eur Acad Dermatol Venereol 2020; 34:239.
- Oetjen LK, Mack MR, Feng J, et al. Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. Cell 2017; 171:217.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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