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What Treatments Work for Anemia of Chronic Disease?
Published: Jan 29, 2024
Treating anemia of chronic disease can be challenging. Let's examine the available therapies and their effectiveness.
Treating the Root Cause
The most effective way to manage anemia of chronic disease (ACD) is to treat the underlying condition causing it. This could involve managing infections, reducing inflammation, or treating chronic diseases like rheumatoid arthritis or cancer. By addressing these root causes, the symptoms of ACD often improve.
Role of Iron and ESAs
Iron supplements are considered when there is a true deficiency, but care is taken due to the risk of excess iron worsening the condition. Erythropoiesis-stimulating agents (ESAs) might be used in specific cases to boost red blood cell production, especially in chronic kidney disease or cancer patients undergoing treatment.
When Transfusions Are Needed
In severe cases, blood transfusions may be required to rapidly increase red blood cell levels. This is typically reserved for life-threatening situations when other treatments are not viable or are taking too long to take effect.
Frequently Asked Questions
Treat the underlying condition causing ACD.
Yes, but only if there's an iron deficiency.
In severe, life-threatening anemia cases.
Finding Solutions
Managing ACD involves a multi-faceted approach focusing on the root cause.
References
- Weiss G, Schett G. Anaemia in inflammatory rheumatic diseases. Nat Rev Rheumatol 2013; 9:205.
- Macdougall IC, Bock AH, Carrera F, et al. FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia. Nephrol Dial Transplant 2014; 29:2075.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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