What's the Best Treatment for Severe Eczema?
Published: Aug 18, 2024
Managing severe eczema can be daunting, but understanding available treatments can make a significant difference.
Contents
Biologic Treatments
Biologic drugs like dupilumab and tralokinumab are game-changers for severe eczema. These medications target specific pathways in the immune system, helping to reduce the frequency and severity of flare-ups with fewer side effects compared to traditional treatments.
Phototherapy: A Light Solution
Phototherapy, or light therapy, is another effective option for severe eczema. It involves exposing the skin to ultraviolet light under medical supervision. This treatment can reduce inflammation and improve skin health, offering relief when other treatments fall short.

Systemic Medications
For those who do not respond to topical treatments, systemic medications like cyclosporine, methotrexate, or oral JAK inhibitors might be recommended. These medications work throughout the body to control inflammation and improve eczema symptoms, though they come with a higher risk of side effects.
Frequently Asked Questions
Biologics target specific immune pathways to reduce flare-ups.
It uses UV light to reduce skin inflammation and improve health.
Yes, they control inflammation but may have more side effects.
Key Takeaways
Are these treatments the answer to your severe eczema woes?
References
- Davis DMR, Drucker AM, Alikhan A, et al. Guidelines of care for the management of atopic dermatitis in adults with phototherapy and systemic therapies. J Am Acad Dermatol 2024; 90:342.
- Chu AWL, Wong MM, Rayner DG, et al. Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials. J Allergy Clin Immunol 2023; 152:1470.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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