What is Microcytosis and Why Should You Care?
Published: Nov 24, 2023
Microcytosis refers to red blood cells that are smaller than usual, which can indicate underlying health issues. Understanding the causes and implications of microcytosis is crucial for maintaining good health.
Contents
Understanding Microcytosis
Microcytosis is a condition where red blood cells (RBCs) are smaller than normal. This is often measured by the mean corpuscular volume (MCV), with values below 80 femtoliters indicating microcytosis. It may suggest various underlying conditions, particularly those affecting hemoglobin production.
Common Causes
The three most common causes of microcytosis include iron deficiency anemia, thalassemia, and anemia of chronic disease. Iron deficiency is often seen in individuals with inadequate nutrition or chronic blood loss. Thalassemia is a genetic condition affecting hemoglobin production, while chronic inflammation can lead to anemia of chronic disease.

Diagnosis and Evaluation
Diagnosis of microcytosis involves blood tests that measure RBC size and hemoglobin content. Evaluating the complete blood count and other indices can help distinguish between different causes. A peripheral blood smear may reveal variations in RBC size and shape, providing additional diagnostic clues.
Frequently Asked Questions
Microcytosis is a condition where red blood cells are smaller than usual.
Common causes include iron deficiency, thalassemia, and anemia of chronic disease.
It is diagnosed through blood tests measuring RBC size and hemoglobin content.
Yes, it can indicate underlying conditions needing medical attention.
Wrapping Up
Understanding microcytosis can guide you toward addressing potential health issues early.
References
- Fulgoni VL 3rd, et al., Am J Clin Pathol 2019; 151:128.
- Staffa SJ, et al., Am J Hematol 2020; 95:E255.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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