What Is Chronic Spontaneous Urticaria? The Mysterious Skin Condition Explained
Published: Dec 07, 2023

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on December 7th, 2023.
Chronic spontaneous urticaria (CSU) is a puzzling skin condition that causes recurring hives and swelling. It affects about 1% of people and can significantly impact quality of life.
Contents
What Does CSU Look Like?
CSU causes itchy, red welts on the skin called hives. These hives can appear anywhere on the body and typically last less than 24 hours before fading. Some people also experience swelling of the lips, eyelids, or other body parts, known as angioedema. The hives and swelling occur repeatedly for 6 weeks or longer without an obvious trigger.
Who Gets CSU?
CSU can affect anyone but is more common in adults, especially women. It often starts between ages 20-40. While the exact cause is unknown, CSU is associated with autoimmune diseases and thyroid disorders in some cases. However, for most people, no underlying cause is found.

How Is CSU Diagnosed?
Doctors diagnose CSU based on symptoms and medical history. There's no specific test for CSU. Basic blood tests are often done to rule out other conditions. A skin biopsy is rarely needed unless the doctor suspects a different condition like urticarial vasculitis.
Frequently Asked Questions
No, CSU cannot be spread from person to person.
There's no cure, but treatments can control symptoms.
Usually not, though some things may worsen symptoms.
Stress may worsen symptoms but doesn't cause CSU.
Key Takeaways
While CSU remains mysterious, ongoing research offers hope for better understanding and treatment of this challenging condition.
Wondering if you might have CSU? Chat with Doctronic to learn more about your symptoms and treatment options.Related Articles
References
Zuberbier T, et al. Allergy. 2018;73(7):1393-1414.
Greaves M. J Allergy Clin Immunol. 2000;105(4):664-672.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.