Doctronic navigation menu Log In
Doctronic navigation menu

Contents
  • What Causes VWD?
  • What Are the Symptoms?
  • How is VWD Diagnosed?
  • What Are the Different Types?

Von Willebrand Disease: The Most Common Bleeding Disorder You've Never Heard Of

Von Willebrand Disease: The Most Common Bleeding Disorder You've Never Heard Of

What's This About?

Von Willebrand Disease (VWD) is the most common inherited bleeding disorder, affecting up to 1% of the population. Yet many people have never heard of it.
Contents
  • What Causes VWD?
  • What Are the Symptoms?
  • How is VWD Diagnosed?
  • What Are the Different Types?

What Causes VWD?

VWD is caused by problems with a protein in your blood called von Willebrand factor (VWF). This protein helps your blood clot. In VWD, you either don't have enough VWF, or the VWF you have doesn't work properly. It's like trying to seal an envelope with weak glue - it just doesn't stick well enough to stop the bleeding.

What Are the Symptoms?

People with VWD may bruise easily or have frequent nosebleeds. Women might have very heavy periods. Bleeding after dental work or surgery can also be a problem. In severe cases, people might have bleeding in their joints or digestive tract. Think of it like a leaky faucet - the blood keeps flowing when it should stop.
Von Willebrand Disease (VWD) is a common inherited bleeding disorder caused by a deficiency or dysfunction of the von Willebrand factor, a protein essential for blood clotting.

How is VWD Diagnosed?

Diagnosing VWD can be tricky. Doctors will ask about your bleeding history and family history. They'll also do blood tests to check your VWF levels and how well it's working. It's like being a detective - they're looking for clues to solve the mystery of your bleeding.

What Are the Different Types?

There are three main types of VWD. Type 1 is the most common and mildest form. Type 2 has several subtypes and involves VWF that doesn't work properly. Type 3 is the rarest and most severe form, where VWF is almost completely missing. It's like having different models of the same car - they all have issues, but some run better than others.

FAQs

Is VWD life-threatening?

Usually not, but severe cases can be dangerous if not treated.

Can VWD be cured?

There's no cure, but treatments can help manage symptoms.

Is VWD only found in women?

No, it affects both men and women equally.

Can you develop VWD later in life?

VWD is inherited, but symptoms may appear or worsen with age.

How is VWD treated?

Treatments include medications, nasal sprays, and sometimes infusions.

The Bottom Line

While VWD can be challenging, with proper diagnosis and treatment, most people can lead normal, active lives.
If you're concerned about unusual bleeding, talk to Doctronic about getting tested for VWD.
Additional References
  1. Nichols WL, et al. von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA). Haemophilia 2008; 14:171.
  2. James PD, et al. ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease. Blood Adv 2021; 5:280.
  3. Sharma R, Flood VH. Advances in the diagnosis and treatment of Von Willebrand disease. Blood 2017; 130:2386.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.