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Unmasking the Risks: Potential Side Effects of Parkinson's Medications
Published: Dec 21, 2023
While Parkinson's medications can greatly improve symptoms, they can also cause side effects. Understanding these risks is crucial for patients and caregivers.
Common Side Effects of Dopaminergic Drugs
Medications that increase dopamine levels, like levodopa and dopamine agonists, can cause nausea, dizziness, and sleepiness. These often improve over time. Some people may experience hallucinations or confusion, especially at higher doses or in older patients. Orthostatic hypotension (a drop in blood pressure when standing) can also occur.
Motor Complications: Dyskinesias and Fluctuations
Long-term use of levodopa can lead to involuntary movements called dyskinesias. Some patients also experience 'wearing off,' where medication effects fade before the next dose. These motor complications affect about half of patients after 5-10 years of treatment. Younger patients may be at higher risk.
Impulse Control Disorders: A Hidden Risk
Dopamine agonists, in particular, can sometimes lead to impulse control disorders. These may include compulsive gambling, shopping, eating, or sexual behavior. It's estimated that up to 50% of patients on long-term dopamine agonist therapy may develop these issues. Patients and families should be aware of this risk and report any unusual behavior changes.
Frequently Asked Questions
No, but they're common. Many can be managed or minimized.
Many improve with dose adjustments or medication changes.
Never stop suddenly. Always consult your doctor first.
Balancing Act
Managing Parkinson's often involves balancing symptom control with side effect risks.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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