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Understanding MGUS Risk Factors: Are You at Risk?
Published: Dec 22, 2023
MGUS might not have symptoms, but certain factors can increase the risk of developing it. Knowing these can help you stay informed about your health.
Age and Ethnicity
MGUS is more common as people age, particularly after 50, with a higher prevalence in African Americans. Studies suggest that genetic predisposition might play a role, as demonstrated by higher rates in people with a family history of MGUS or related conditions.
Gender Differences
Men are more likely to develop MGUS than women, with studies indicating this trend across various populations. The reasons for these gender differences aren't fully understood, but they emphasize the importance of regular health screenings, especially for men over 50.
Environmental and Lifestyle Factors
Although no direct environmental causes have been established, some studies suggest occupational exposure and lifestyle choices could influence MGUS risk. Maintaining a healthy lifestyle might help manage the risk, although it hasn't been proven to prevent MGUS.
Frequently Asked Questions
Older adults, particularly over age 50, and African Americans are at higher risk.
Yes, men are at a higher risk than women.
A healthy lifestyle might help, but it hasn't been proven to prevent MGUS.
The Bottom Line
Understanding your risk factors for MGUS is a key step in managing your health.
References
- Kyle RA, Rajkumar SV. Monoclonal gammopathy of undetermined significance. Br J Haematol 2006; 134:573.
- Landgren O, Gridley G, Turesson I, et al. Risk of monoclonal gammopathy of undetermined significance (MGUS) and subsequent multiple myeloma among African American and white veterans in the United States. Blood 2006; 107:904.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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