Uncovering the Hidden Risk Factors of Primary Aldosteronism
Published: Dec 29, 2023
Primary aldosteronism isn't just about high blood pressure; it's a potential risk factor for other health issues. Here's what you need to know.
Contents
The Role of Aldosterone
Aldosterone is a hormone that helps regulate blood pressure by controlling sodium and potassium levels. In primary aldosteronism, excess aldosterone leads to high blood pressure and can disrupt normal heart and kidney functions. This imbalance can make the condition a hidden risk factor for more serious cardiovascular problems.
Link to Cardiovascular Diseases
Patients with primary aldosteronism have a higher risk of cardiovascular conditions than those with regular hypertension. Increased aldosterone levels can lead to heart complications like left ventricular hypertrophy and atrial fibrillation. Managing aldosterone levels is crucial to reducing these risks and improving heart health.

Impacts on Kidney Function
Primary aldosteronism can also affect the kidneys by increasing glomerular filtration rate and urinary albumin excretion. This can lead to kidney damage if left untreated. However, with proper treatment, these changes are often reversible, highlighting the importance of early diagnosis and management.
Frequently Asked Questions
Excess aldosterone can lead to heart issues like hypertrophy and atrial fibrillation.
Yes, it can lead to increased filtration and potential kidney damage.
Yes, with proper treatment, kidney function changes are often reversible.
It's the thickening of the heart's left ventricular wall, often due to high blood pressure.
The Bottom Line
Are you aware of how primary aldosteronism could be impacting your health?
References
- Monticone S, et al. Cardiovascular events in primary aldosteronism: Lancet Diabetes Endocrinol 2018; 6:41.
- Pitt B, et al. Eplerenone in left ventricular dysfunction: N Engl J Med 2003; 348:1309.
- Williams JS, et al. 50th anniversary of aldosterone: J Clin Endocrinol Metab 2003; 88:2364.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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