Treatment Options for Ulcerative Colitis: From Medications to Surgery
Published: May 09, 2024
Treating ulcerative colitis aims to induce and maintain remission, improve quality of life, and prevent complications. Various options are available, from medications to surgical interventions.
Contents
Medications
The cornerstone of ulcerative colitis treatment is medication. Aminosalicylates like mesalamine are often used for mild to moderate cases. Corticosteroids can quickly reduce inflammation during flares but aren't used long-term due to side effects. Immunomodulators and biologics target the immune system to control inflammation in more severe cases. These medications work like a fire brigade, putting out the inflammatory 'fire' in your colon.
Dietary and Lifestyle Changes
While diet doesn't cause ulcerative colitis, certain foods may trigger symptoms in some people. Working with a dietitian to identify trigger foods can be helpful. Stress reduction techniques like meditation or yoga may help manage flares. Regular exercise, when possible, can improve overall health and may help reduce inflammation.

Surgical Options
In cases where medications aren't effective or complications develop, surgery may be necessary. The most common procedure is removal of the colon and rectum (proctocolectomy) with creation of an internal pouch (ileal pouch-anal anastomosis). This eliminates the disease and allows for relatively normal bowel function. About 25-30% of ulcerative colitis patients eventually require surgery.
Frequently Asked Questions
No, but medications can induce and maintain long-term remission.
They can have side effects, but are generally safe under medical supervision.
No, many patients have surgery without needing a permanent ostomy.
Personalized Approach
Treatment for ulcerative colitis is highly individualized, and what works best can vary from person to person and may change over time.
References
- Rubin DT, et al. ACG Clinical Guideline: Ulcerative Colitis in Adults. Am J Gastroenterol 2019; 114:384.
- Ungaro R, et al. Ulcerative colitis. Lancet 2017; 389:1756.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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