Treating Uric Acid Stones: Effective Therapies
Treating Uric Acid Stones: Effective Therapies
Why It Matters
Uric acid stones can be incredibly painful, but effective treatments are available. Learn about the therapies that can help.
Contents
- Alkalinization Therapy
- Xanthine Oxidase Inhibitors
Alkalinization Therapy
Alkalinization therapy involves using medications like potassium citrate to raise urine pH. This treatment makes uric acid more soluble, reducing the risk of stone formation. It's a non-invasive option that can dissolve existing stones and prevent new ones.
Xanthine Oxidase Inhibitors
For those with recurrent stones, xanthine oxidase inhibitors like allopurinol can be used. These medications lower uric acid production, helping to prevent stone formation. They are especially useful for patients who cannot maintain a high urine pH.
FAQs
What is alkalinization therapy?
It's a treatment to increase urine pH and make uric acid more soluble.
When are xanthine oxidase inhibitors used?
They're used for recurrent stones or when urine pH can't be maintained.
Can these therapies dissolve stones?
Yes, alkalinization can dissolve existing uric acid stones.
The Bottom Line
With the right treatment, uric acid stones can be managed effectively, reducing pain and recurrence.
Additional References
- Pak CY, Sakhaee K, Peterson RD, et al. Biochemical profile of idiopathic uric acid nephrolithiasis. Kidney Int 2001; 60:757.
- Becker MA, Kisicki J, Khosravan R, et al. Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers. Nucleosides Nucleotides Nucleic Acids 2004; 23:1111.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.