Therapies for Diabetic Autonomic Neuropathy: What's Available?
Published: Jan 18, 2024
Diabetic autonomic neuropathy (DAN) can significantly impact quality of life. Learn about therapeutic options available to manage this condition effectively.
Contents
Glycemic Control Therapy
Improving blood sugar control is a cornerstone of managing DAN. Gradual reduction in glycemic levels helps prevent additional nerve damage. Intensive insulin therapy has shown benefits, particularly in reducing cardiovascular autonomic neuropathy in type 1 diabetes.
Symptomatic Treatments
Medications can be used to relieve specific symptoms of DAN, such as dizziness and heart palpitations. Options include fludrocortisone and midodrine for orthostatic hypotension. These treatments provide symptom relief and improve daily functioning.

Non-Pharmacologic Interventions
Lifestyle modifications like increased fluid intake and dietary adjustments can aid in symptom management. Elevating the head of the bed and avoiding quick changes in posture can also help reduce symptoms. These non-drug approaches are often the first step in managing milder symptoms.
Frequently Asked Questions
Glycemic control is key to managing DAN.
Yes, medications like fludrocortisone can help.
Absolutely, they can help manage symptoms effectively.
It reduces cardiovascular autonomic neuropathy risk.
Wrapping Up
Effective management of DAN involves a combination of therapies tailored to individual needs.
References
- Pop-Busui R, Low PA, Waberski BH, et al. Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC). Circulation 2009; 119:2886.
- Gaede P, Vedel P, Larsen N, et al. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med 2003; 348:383.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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