Spotting the Signs: Symptoms of Parvovirus B19
Published: Mar 30, 2024
Recognizing the symptoms of parvovirus B19 is key to understanding its impact. From harmless rashes to serious anemia, here's what you need to know.
Contents
Classic Symptoms in Children
In children, parvovirus B19 typically causes erythema infectiosum, also known as fifth disease. This presents as a bright red rash on the cheeks, often referred to as the 'slapped cheek' rash. This rash can spread to the trunk and limbs, creating a lace-like pattern. Children may also have a mild fever and feel unwell.
Adult Manifestations
Adults infected with parvovirus B19 might not develop the classic rash but can experience joint pain, particularly in the hands, wrists, and knees. This joint pain is more common in women and can last for weeks. Some adults might also feel fatigued or develop a mild flu-like illness without a rash.

Severe Cases in Vulnerable Populations
For those with chronic blood disorders, parvovirus B19 can lead to a severe drop in red blood cell production, known as transient aplastic crisis, causing extreme fatigue and anemia. Pregnant women are at risk for complications affecting the fetus, such as severe anemia or miscarriage.
Uncommon but Possible: Neurologic Symptoms
Though rare, parvovirus B19 can lead to neurological issues like encephalitis in both children and adults. These symptoms may coincide with a rash or anemia, making early diagnosis and treatment crucial.
Frequently Asked Questions
The 'slapped cheek' rash is the most common symptom in children.
Adults may not get a rash but often experience joint pain.
Yes, especially in those with existing blood disorders.
Yes, though rare, symptoms like encephalitis can occur.
It can cause fetal complications, so exposure should be monitored.
The Bottom Line
Recognizing parvovirus B19 symptoms early can aid in timely and effective management.
References
- Anderson MJ, Higgins PG, Davis LR, et al. J Infect Dis 1985; 152:257.
- Grilli R, Izquierdo MJ, FariΓ±a MC, et al. J Am Acad Dermatol 1999; 41:793.
- Heegaard ED, Brown KE. Clin Microbiol Rev 2002; 15:485.
- Woolf AD, Campion GV, Chishick A, et al. Arch Intern Med 1989; 149:1153.
- Hayakawa H, Tara M, Niina K, Osame M. Intern Med 2002; 41:295.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
15-min consultation. No hidden costs.
AI Doctor Visit Required
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?