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Red Flags Revealed: Spotting the Symptoms of Acquired Hemophilia A
Published: Jun 06, 2024
Acquired hemophilia A can be a master of disguise, often sneaking up without warning. But knowing the telltale signs can make all the difference in getting a timely diagnosis. Let's unmask the symptoms that could point to this rare but serious bleeding disorder.
Unexpected Bruising
The most common and often first sign of acquired hemophilia A is unusual bruising. We're not talking about small bruises from bumping into furniture. These bruises are often large, sometimes massive, and can appear without any apparent injury. They might start small but expand rapidly, covering large areas of the skin. The bruises are typically soft and painless, unlike the tender bruises from injuries.
Prolonged Bleeding
Another red flag is bleeding that just won't stop. This could be from minor cuts or scrapes that keep oozing, or nosebleeds that go on for hours. Dental procedures or minor surgeries might result in excessive bleeding that's hard to control. Women might notice heavier or longer menstrual periods. The key here is that the bleeding is out of proportion to the injury or situation.
Internal Bleeding
Some of the most dangerous symptoms of acquired hemophilia A are those you can't see. Internal bleeding can occur in muscles, leading to pain, swelling, and sometimes warmth in the affected area. Bleeding into the digestive tract might cause black, tarry stools or blood in the urine. In severe cases, there might be bleeding in the brain, causing symptoms like severe headache, confusion, or stroke-like symptoms.
Unusual Locations
Unlike inherited hemophilia, acquired hemophilia A rarely causes joint bleeding. Instead, it tends to affect soft tissues, muscles, and mucous membranes. Retroperitoneal bleeding (bleeding behind the abdominal cavity) is particularly characteristic and can be life-threatening. Symptoms might include abdominal or back pain, and in severe cases, signs of shock like dizziness or fainting.
Frequently Asked Questions
Yes, they often develop rapidly without warning.
Rarely, it's discovered through routine blood tests before symptoms appear.
No, they can vary widely in type and severity.
Yes, leading to potential delays in diagnosis.
Usually not; proper treatment is needed to control symptoms.
Stay Alert
While these symptoms can be alarming, recognizing them early can lead to faster diagnosis and treatment, potentially saving lives.
References
- Kruse-Jarres R, et al. Acquired hemophilia A: Updated review of evidence and treatment guidance. Am J Hematol. 2017;92(7):695-705.
- Tiede A, et al. International recommendations on the diagnosis and treatment of acquired hemophilia A. Haematologica. 2020;105(7):1791-1801.
- Knoebl P, et al. Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). J Thromb Haemost. 2012;10(4):622-631.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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