Psoriasis and Comorbidities: More Than Skin Deep
Published: Sep 26, 2023
Psoriasis is more than just a skin condition. This chronic inflammatory disease is associated with several other health conditions, known as comorbidities. Understanding these connections is crucial for comprehensive care.
Contents
Cardiovascular Disease and Psoriasis
People with psoriasis have an increased risk of cardiovascular disease. This includes conditions like heart attack, stroke, and atherosclerosis. The link is thought to be due to shared inflammatory pathways. Severe psoriasis appears to carry a higher cardiovascular risk than mild cases.
Metabolic Syndrome and Psoriasis
Psoriasis is associated with a higher prevalence of metabolic syndrome. This cluster of conditions includes obesity, high blood pressure, high blood sugar, and abnormal cholesterol levels. The connection may be due to chronic inflammation and shared genetic factors. Managing these conditions is important for overall health in psoriasis patients.

Psoriatic Arthritis
Up to 30% of people with psoriasis develop psoriatic arthritis, an inflammatory joint condition. It can cause joint pain, stiffness, and swelling. Early diagnosis and treatment of psoriatic arthritis is crucial to prevent joint damage. Patients with psoriasis should be monitored for signs of joint problems.
Mental Health and Quality of Life
Psoriasis can have significant psychological impacts. Depression and anxiety are more common in people with psoriasis. The visible nature of the condition can affect self-esteem and social relationships. Addressing mental health is an important part of comprehensive psoriasis care.
Frequently Asked Questions
Some studies suggest a slightly increased risk for certain cancers.
Yes, managing psoriasis may help reduce inflammation throughout the body.
Risk varies, but all patients should be monitored.
Regular screenings are recommended; frequency depends on individual risk factors.
Yes, healthy diet, exercise, and stress management can be beneficial.
A Holistic Approach
Managing psoriasis effectively requires attention to both skin symptoms and potential comorbidities for optimal overall health.
References
- Takeshita J, et al. Psoriasis and comorbid diseases: Epidemiology. J Am Acad Dermatol. 2017;76(3):377-390.
- Oliveira Mde F, et al. Psoriasis: classical and emerging comorbidities. An Bras Dermatol. 2015;90(1):9-20.
- Yeung H, et al. Psoriasis severity and the prevalence of major medical comorbidity: a population-based study. JAMA Dermatol. 2013;149(10):1173-9.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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