Peptic Ulcers: What Really Causes Them?

Published: Jan 01, 2024

Understanding what causes peptic ulcers can help prevent them. Let's uncover the main culprits behind this common ailment.

The Role of H. Pylori

Helicobacter pylori, or H. pylori, is a bacteria found in many people’s stomachs. It can lead to inflammation and, eventually, ulcers. Testing for and treating H. pylori is crucial in managing peptic ulcer disease because eradicating this bacteria can prevent ulcers from coming back.

Medicines That Might Be Harmful

Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen are common pain relievers that can irritate the stomach lining. Long-term or heavy use increases the risk of developing ulcers. Corticosteroids, especially when combined with NSAIDs, can also heighten this risk.

A peptic ulcer is a sore on the lining of the stomach or the first part of the small intestine. It is often caused by the Helicobacter pylori infection or prolonged use of NSAIDs.

Other Unusual Causes

While less common, certain systemic diseases like sarcoidosis or Crohn's disease can also lead to peptic ulcers. In these cases, the ulcers are a result of the primary disease affecting the stomach lining. Biopsies and other diagnostic tests help identify these rarer causes.

Frequently Asked Questions

H. pylori infection is a leading cause of peptic ulcers.

Yes, NSAIDs like aspirin and ibuprofen can lead to ulcers.

Yes, certain diseases like Crohn's can also cause ulcers.

Through tests like urea breath tests or stool antigen assays.

Key Takeaways

Knowing the causes of peptic ulcers can aid in prevention and treatment.

Discuss with Doctronic how you can reduce your risk of peptic ulcers.

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References

Malfertheiner P, Megraud F, O'Morain CA, et al. Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report. Gut 2017; 66:6.

Tseng CL, Chen YT, Huang CJ, et al. Short-term use of glucocorticoids and risk of peptic ulcer bleeding: a nationwide population-based case-crossover study. Aliment Pharmacol Ther 2015; 42:599.

Always discuss health information with your healthcare provider.