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Is Your High Calcium Level a Sign of Primary Hyperparathyroidism?
Published: May 14, 2024
Primary hyperparathyroidism often sneaks up on people, but high calcium levels can be a telltale sign. Discover what this condition entails and why it's important to diagnose and manage it effectively.
Understanding Primary Hyperparathyroidism
Primary hyperparathyroidism (PHPT) is a condition where the parathyroid glands secrete too much hormone, leading to elevated calcium levels in the blood. This condition is often discovered during routine blood tests when high calcium levels are found. Despite its often asymptomatic nature, PHPT can lead to serious health issues if left untreated.
Diagnosing PHPT
Diagnosing PHPT involves confirming high calcium levels and measuring parathyroid hormone (PTH) levels. If PTH levels are elevated or normal despite high calcium levels, PHPT is likely. Further tests, like 24-hour urinary calcium excretion, can help differentiate PHPT from other conditions like familial hypocalciuric hypercalcemia (FHH).
Secondary Conditions and PHPT
PHPT can be complicated by secondary conditions such as vitamin D deficiency and kidney disease, which must be ruled out to confirm a PHPT diagnosis. Vitamin D deficiency can mask hypercalcemia, making diagnosis tricky, while kidney disease can influence calcium levels and PTH secretion.
Frequently Asked Questions
It's a condition where the parathyroid glands overproduce hormone, raising calcium levels.
Diagnosis involves high calcium levels and elevated or normal PTH levels despite hypercalcemia.
Yes, many people don't experience symptoms initially.
Vitamin D deficiency can mask PHPT symptoms, complicating diagnosis.
Some forms of PHPT have a genetic component, especially in familial cases.
Key Takeaways
Could your unexplained high calcium levels be a sign of PHPT?
References
- Bilezikian JP, Khan AA, Silverberg SJ, et al. Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop. J Bone Miner Res 2022; 37:2293.
- Minisola S, Arnold A, Belaya Z, et al. Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism. J Bone Miner Res 2022; 37:2315.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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