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Is Your Family History Putting You at Risk for Eczema?
Published: Jan 14, 2024
Eczema doesn't just appear out of nowhere; family history and genetics play a significant role in its development.
Genetic Factors
Genetics are a major component in the risk for eczema. A family history of atopy, such as eczema, asthma, or allergic rhinitis, significantly increases one's risk. Mutations in the FLG gene, which is crucial for skin barrier function, are also strongly linked to eczema.
Environmental Influences
Beyond genetics, environmental factors also impact eczema risk. Urban living, air pollution, and changes in humidity can exacerbate the condition. The 'hygiene hypothesis' suggests that limited exposure to microorganisms in early life may increase eczema risk.
Impact of Lifestyle
Lifestyle choices can also influence eczema. Frequent use of harsh soaps, poor diet, and stress are known to contribute to flare-ups. Identifying and mitigating these factors can help manage eczema risk.
Frequently Asked Questions
Family history of allergies raises eczema risk.
Urban living and pollution can worsen eczema.
Yes, avoiding harsh soaps and stress can help.
It suggests limited early exposure to germs increases eczema risk.
Wrapping Up
Understanding your genetic and environmental risks can guide effective eczema management.
References
- Williams H, Flohr C. How epidemiology has challenged 3 prevailing concepts about atopic dermatitis. J Allergy Clin Immunol 2006; 118:209.
- Irvine AD, McLean WH, Leung DY. Filaggrin mutations associated with skin and allergic diseases. N Engl J Med 2011; 365:1315.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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