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Is Your Cortisol Level Telling You a Different Story? Understanding Cushing Syndrome
Published: Sep 03, 2023
Cushing syndrome is a condition caused by excessive cortisol in the body. Understanding its causes can be the key to effective diagnosis and treatment.
What is Cushing Syndrome?
Cushing syndrome occurs when your body is exposed to high levels of the hormone cortisol for an extended period. This can be due to the body making too much cortisol or from external sources like medication. The condition can lead to symptoms like weight gain, high blood pressure, and mood changes, making it crucial to identify the source of the excess cortisol.
ACTH-Dependent vs. Independent Cushing Syndrome
Determining whether Cushing syndrome is ACTH-dependent involves checking if the condition is caused by a tumor in the pituitary gland or elsewhere that produces ACTH. ACTH-independent syndrome means the adrenal glands are producing too much cortisol on their own. This distinction is vital for determining the appropriate treatment approach.
Testing for Cushing Syndrome
To diagnose Cushing syndrome, doctors often measure levels of cortisol in urine, saliva, or blood. They may also conduct imaging tests or stimulation tests to determine whether the condition is ACTH-dependent or independent. These tests help pinpoint the source of excess cortisol, guiding further treatment.
Frequently Asked Questions
Cushing syndrome is caused by excessive cortisol, often due to tumors or prolonged steroid use.
ACTH stimulates cortisol production, and its levels can indicate whether Cushing syndrome is ACTH-dependent or independent.
Symptoms include weight gain, high blood pressure, and mood swings.
It is diagnosed through cortisol level tests and imaging studies.
Yes, treatment depends on the underlying cause and may involve surgery, medication, or lifestyle changes.
Key Takeaways
Understanding the cause of Cushing syndrome is crucial for effective treatment.
References
- Lacroix A, et al. Cushing's syndrome. Lancet 2015; 386:913.
- Sharma ST. AN INDIVIDUALIZED APPROACH TO THE EVALUATION OF CUSHING SYNDROME. Endocr Pract 2017; 23:726.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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