How to Treat Penicillin Allergies Safely
Published: Jun 04, 2024
Managing penicillin allergies involves careful diagnosis and treatment to avoid serious reactions. Learn how healthcare providers tackle these challenges.
Contents
Immediate Steps for Suspected Allergies
If a penicillin allergy is suspected, the first step is to stop taking the drug and inform a healthcare provider. Depending on the severity of the symptoms, treatment may involve antihistamines or, in severe cases, corticosteroids to manage the reaction.
Long-Term Management Strategies
For those with a confirmed penicillin allergy, healthcare providers often recommend avoiding penicillin and related antibiotics. In some cases, allergy specialists may perform desensitization procedures, which gradually increase the dose of penicillin to help the body tolerate it.

When to Consider Allergy Testing
Allergy testing is particularly important for individuals who need to use penicillin for future medical treatments. Tests can include skin tests or controlled oral challenges to determine if penicillin can be safely reintroduced.
Frequently Asked Questions
Stop taking the drug and contact a healthcare provider immediately.
Yes, treatments include antihistamines, corticosteroids, and possibly desensitization.
Testing helps confirm allergies and guides safe use of antibiotics.
Yes, many people lose their penicillin allergy over time.
The Bottom Line
Safe management of penicillin allergies requires accurate diagnosis and appropriate treatment.
References
- Patel BM. Skin rash with infectious mononucleosis and ampicillin. Pediatrics 1967; 40:910.
- Blanca-Lรณpez N, et al. Skin testing and drug provocation in children. Allergy 2009; 64:229.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
15-min consultation. No hidden costs.
AI Doctor Visit Required
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?