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How to Beat Resistant Hypertension with Medications
Published: Jan 15, 2024
Taming resistant hypertension often requires a careful mix of medications. Discover the step-by-step approach to finding the right combination for you.
The Core Medication Trio
The first line of defense includes a combination of an ACE inhibitor or ARB, a calcium channel blocker, and a diuretic. This trio works by targeting different pathways to lower blood pressure effectively. Adjustments in doses and drug types might be needed based on individual response.
Adding a Mineralocorticoid Receptor Antagonist
If the core medication trio isn't enough, a mineralocorticoid receptor antagonist like spironolactone can be added. This medication helps tackle resistant hypertension by addressing hormonal imbalances. Monitoring for side effects, like increased potassium levels, is essential when using these drugs.
Exploring Additional Medication Options
For some patients, even more medications might be necessary. Options include beta blockers, alpha-1 antagonists, or direct vasodilators. The choice depends on personal health factors and any side effects experienced from current treatments.
Frequently Asked Questions
A combination of an ACE inhibitor or ARB, a calcium channel blocker, and a diuretic.
It's added when the initial medication trio doesn't control blood pressure.
Yes, monitoring for side effects like high potassium levels is important.
Yes, additional options like beta blockers may be necessary.
The Bottom Line
Finding the right medication mix is key to managing resistant hypertension effectively.
References
- Giacona JM, Kositanurit W, Vongpatanasin W. Management of Resistant Hypertension-An Update. JAMA Intern Med 2024; 184:433.
- Chapman N, Dobson J, Wilson S, et al. Effect of spironolactone on blood pressure in subjects with resistant hypertension. Hypertension 2007; 49:839.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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