How is G6PD Deficiency Diagnosed? Tests You Should Know About

Screening Tests

Initial screening for G6PD deficiency involves qualitative tests that measure the enzyme's activity. These tests are often the first step and can provide quick results. They work by detecting the reduction of NADP to NADPH, a key function of the G6PD enzyme. If a screening test is positive, further confirmatory testing is usually recommended.

Confirmatory Testing

Confirmatory tests involve a quantitative analysis of G6PD enzyme activity. These tests measure the exact amount of enzyme present in red blood cells. Results are expressed in units per gram of hemoglobin, providing a detailed view of enzyme levels. Confirmatory testing is essential for accurate diagnosis and guiding management decisions.

When to Test

Testing for G6PD deficiency is advised for individuals with unexplained anemia or newborns with jaundice. It is also important before administering certain medications that can cause oxidative stress. If someone experiences hemolytic symptoms, especially after taking certain drugs, testing should be considered.

Frequently Asked Questions

Key Takeaways

Proper testing ensures accurate diagnosis and management of G6PD deficiency.

Related Articles

• What is G6PD Deficiency and How Does It Affect You?
• Are These Medications Safe for You? A Guide for G6PD Deficient Individuals
• The Foods You Should Avoid If You Have G6PD Deficiency
• Managing G6PD Deficiency: What You Need to Know

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